CHED_BURP0
ID CHED_BURP0 Reviewed; 234 AA.
AC A3P0N1;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 03-APR-2007, sequence version 1.
DT 03-AUG-2022, entry version 63.
DE RecName: Full=Probable chemoreceptor glutamine deamidase CheD {ECO:0000255|HAMAP-Rule:MF_01440};
DE EC=3.5.1.44 {ECO:0000255|HAMAP-Rule:MF_01440};
GN Name=cheD {ECO:0000255|HAMAP-Rule:MF_01440};
GN OrderedLocusNames=BURPS1106A_3932;
OS Burkholderia pseudomallei (strain 1106a).
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; pseudomallei group.
OX NCBI_TaxID=357348;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1106a;
RX PubMed=20333227; DOI=10.1093/gbe/evq003;
RA Losada L., Ronning C.M., DeShazer D., Woods D., Fedorova N., Kim H.S.,
RA Shabalina S.A., Pearson T.R., Brinkac L., Tan P., Nandi T., Crabtree J.,
RA Badger J., Beckstrom-Sternberg S., Saqib M., Schutzer S.E., Keim P.,
RA Nierman W.C.;
RT "Continuing evolution of Burkholderia mallei through genome reduction and
RT large-scale rearrangements.";
RL Genome Biol. Evol. 2:102-116(2010).
CC -!- FUNCTION: Probably deamidates glutamine residues to glutamate on
CC methyl-accepting chemotaxis receptors (MCPs), playing an important role
CC in chemotaxis. {ECO:0000255|HAMAP-Rule:MF_01440}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + L-glutaminyl-[protein] = L-glutamyl-[protein] + NH4(+);
CC Xref=Rhea:RHEA:16441, Rhea:RHEA-COMP:10207, Rhea:RHEA-COMP:10208,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:29973,
CC ChEBI:CHEBI:30011; EC=3.5.1.44; Evidence={ECO:0000255|HAMAP-
CC Rule:MF_01440};
CC -!- SIMILARITY: Belongs to the CheD family. {ECO:0000255|HAMAP-
CC Rule:MF_01440}.
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DR EMBL; CP000572; ABN91191.1; -; Genomic_DNA.
DR RefSeq; WP_004198646.1; NC_009076.1.
DR AlphaFoldDB; A3P0N1; -.
DR SMR; A3P0N1; -.
DR EnsemblBacteria; ABN91191; ABN91191; BURPS1106A_3932.
DR GeneID; 56593993; -.
DR KEGG; bpl:BURPS1106A_3932; -.
DR HOGENOM; CLU_087854_0_0_4; -.
DR OMA; VGMADLN; -.
DR Proteomes; UP000006738; Chromosome I.
DR GO; GO:0050568; F:protein-glutamine glutaminase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-UniRule.
DR CDD; cd16352; CheD; 1.
DR Gene3D; 3.30.1330.200; -; 1.
DR HAMAP; MF_01440; CheD; 1.
DR InterPro; IPR038592; CheD-like_sf.
DR InterPro; IPR005659; Chemorcpt_Glu_NH3ase_CheD.
DR InterPro; IPR011324; Cytotoxic_necrot_fac-like_cat.
DR PANTHER; PTHR35147; PTHR35147; 1.
DR Pfam; PF03975; CheD; 1.
DR SUPFAM; SSF64438; SSF64438; 1.
PE 3: Inferred from homology;
KW Chemotaxis; Hydrolase.
FT CHAIN 1..234
FT /note="Probable chemoreceptor glutamine deamidase CheD"
FT /id="PRO_1000068547"
SQ SEQUENCE 234 AA; 25682 MW; 8BAA17C949315C22 CRC64;
MSGLPIATNL YFDAHFHRHG VKLLPNEFYT TREDMVLVTV LGSCVAACLH DPIGRIGGMN
HFMLPDDGAD PSAAASESMR YGAYAMEVLI NELIKAGGRR ERFEAKVFGG AAVLAGMTTI
NIGDRNADFV RRYLALERIR ITAEDLQGVH PRKVAFMPHT GQAMVKKLRV QAPDVAAREA
ALAREAVDPH GERAPRVRPR VELFGTPAPK AQAKPRIELF GMRATQPATR KQEA