ID   CHEF1_HALS3             Reviewed;         290 AA.
AC   B0R4J3;
DT   14-MAY-2014, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Taxis protein CheF1;
GN   Name=cheF1; OrderedLocusNames=OE_2402F;
OS   Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halobacteriaceae; Halobacterium.
OX   NCBI_TaxID=478009;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29341 / DSM 671 / R1;
RX   PubMed=18313895; DOI=10.1016/j.ygeno.2008.01.001;
RA   Pfeiffer F., Schuster S.C., Broicher A., Falb M., Palm P., Rodewald K.,
RA   Ruepp A., Soppa J., Tittor J., Oesterhelt D.;
RT   "Evolution in the laboratory: the genome of Halobacterium salinarum strain
RT   R1 compared to that of strain NRC-1.";
RL   Genomics 91:335-346(2008).
RN   [2]
RP   FUNCTION, INTERACTION WITH CHE AND FLA PROTEINS, DISRUPTION PHENOTYPE, AND
RP   GENE NAME.
RC   STRAIN=ATCC 29341 / DSM 671 / R1;
RX   PubMed=19291314; DOI=10.1186/1471-2180-9-56;
RA   Schlesner M., Miller A., Streif S., Staudinger W.F., Muller J.,
RA   Scheffer B., Siedler F., Oesterhelt D.;
RT   "Identification of Archaea-specific chemotaxis proteins which interact with
RT   the flagellar apparatus.";
RL   BMC Microbiol. 9:56-56(2009).
CC   -!- FUNCTION: Involved in taxis signal transduction. Essential for the
CC       ability to control the direction of flagellar rotation. May have a role
CC       between CheY and the flagellum. {ECO:0000269|PubMed:19291314}.
CC   -!- SUBUNIT: Interacts with chemotaxis (Che) proteins as well as flagella
CC       accessory (Fla) proteins. {ECO:0000269|PubMed:19291314}.
CC   -!- DISRUPTION PHENOTYPE: Mutants are unable to switch the direction of
CC       flagellar rotation. Flagella rotate only clockwise, resulting in
CC       exclusively forward swimming cells that are unable to respond to tactic
CC       signals. {ECO:0000269|PubMed:19291314}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AM774415; CAP13658.1; -; Genomic_DNA.
DR   RefSeq; WP_010902684.1; NC_010364.1.
DR   AlphaFoldDB; B0R4J3; -.
DR   SMR; B0R4J3; -.
DR   EnsemblBacteria; CAP13658; CAP13658; OE_2402F.
DR   GeneID; 5952757; -.
DR   GeneID; 62886514; -.
DR   KEGG; hsl:OE_2402F; -.
DR   HOGENOM; CLU_968406_0_0_2; -.
DR   OMA; FMSPAIR; -.
DR   PhylomeDB; B0R4J3; -.
DR   Proteomes; UP000001321; Chromosome.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   InterPro; IPR007381; CheF1/F2.
DR   PANTHER; PTHR42201; PTHR42201; 1.
DR   Pfam; PF04283; CheF-arch; 1.
DR   PIRSF; PIRSF026802; UCP026802; 1.
PE   1: Evidence at protein level;
KW   Chemotaxis.
FT   CHAIN           1..290
FT                   /note="Taxis protein CheF1"
FT                   /id="PRO_0000429071"
SQ   SEQUENCE   290 AA;  31998 MW;  4F0117CF8F8A6BC3 CRC64;
     MSESEYKIAD GSGKFLQAVK DGRRMKDAQW SKGRILLSNK RIVLAGSEGK RNLPLSEVQG
     LSGRHDVNQT VAKVGNYVSI RMTNESVMLV SLGDNTETFE SKLYGALLDQ TELQVKHPAV
     EGGVVTDEQF ERARIKVDES ELSVAMSNGS FVSVELDDVG SAEAASLEVN GDTKPVLKVE
     HTVNRDTSVQ TYFATDSHTA SILESLLTKE AEKSQGSVEL SETEKRVLMA LYSGVSSFEI
     PDFLGMDVDE VESIFERLIE VDVLEEVRKR REVTMKTRGR NIASEAINEE