ID   CHEW_SALTY              Reviewed;         167 AA.
AC   P06110;
DT   01-JAN-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1988, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=Chemotaxis protein CheW;
GN   Name=cheW; OrderedLocusNames=STM1920;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3542987; DOI=10.1016/s0021-9258(19)75814-1;
RA   Stock A., Mottonen J., Chen T., Stock J.;
RT   "Identification of a possible nucleotide binding site in CheW, a protein
RT   required for sensory transduction in bacterial chemotaxis.";
RL   J. Biol. Chem. 262:535-537(1987).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Involved in the transmission of sensory signals from the
CC       chemoreceptors to the flagellar motors.
CC   -!- INTERACTION:
CC       P06110; P65977: recA; NbExp=3; IntAct=EBI-10686956, EBI-10686930;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
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DR   EMBL; J02656; AAA27036.1; -; Genomic_DNA.
DR   EMBL; AE006468; AAL20836.1; -; Genomic_DNA.
DR   PIR; A26143; A26143.
DR   RefSeq; NP_460877.1; NC_003197.2.
DR   RefSeq; WP_000147295.1; NC_003197.2.
DR   AlphaFoldDB; P06110; -.
DR   SMR; P06110; -.
DR   DIP; DIP-61269N; -.
DR   IntAct; P06110; 2.
DR   STRING; 99287.STM1920; -.
DR   PaxDb; P06110; -.
DR   EnsemblBacteria; AAL20836; AAL20836; STM1920.
DR   GeneID; 1253441; -.
DR   KEGG; stm:STM1920; -.
DR   PATRIC; fig|99287.12.peg.2037; -.
DR   HOGENOM; CLU_048995_1_0_6; -.
DR   OMA; CVNIMSV; -.
DR   PhylomeDB; P06110; -.
DR   BioCyc; SENT99287:STM1920-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0006935; P:chemotaxis; IBA:GO_Central.
DR   GO; GO:1903911; P:positive regulation of receptor clustering; IMP:AgBase.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   InterPro; IPR039315; CheW.
DR   InterPro; IPR036061; CheW-like_dom_sf.
DR   InterPro; IPR002545; CheW-lke_dom.
DR   PANTHER; PTHR22617; PTHR22617; 1.
DR   Pfam; PF01584; CheW; 1.
DR   SMART; SM00260; CheW; 1.
DR   SUPFAM; SSF50341; SSF50341; 1.
DR   PROSITE; PS50851; CHEW; 1.
PE   1: Evidence at protein level;
KW   Chemotaxis; Cytoplasm; Reference proteome.
FT   CHAIN           1..167
FT                   /note="Chemotaxis protein CheW"
FT                   /id="PRO_0000198347"
FT   DOMAIN          16..156
FT                   /note="CheW-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00052"
SQ   SEQUENCE   167 AA;  18049 MW;  986F32CE2D931229 CRC64;
     MTGMSNVSKL AGEPSGQEFL VFTLGNEEYG IDILKVQEIR GYDQVTRIAN TPAFIKGVTN
     LRGVIVPIVD LRVKFCEGDV EYDDNTVVIV LNLGQRVVGI VVDGVSDVLS LTAEQIRPAP
     EFAVTLSTEY LTGLGALGER MLILVNIEKL LNSEEMALLD IAASHVA