ID   CHEW_TREPA              Reviewed;         170 AA.
AC   O83453;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Chemotaxis protein CheW;
GN   Name=cheW; OrderedLocusNames=TP_0439;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- FUNCTION: Involved in the transmission of sensory signals from the
CC       chemoreceptors to the flagellar motors. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
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DR   EMBL; AE000520; AAC65426.1; -; Genomic_DNA.
DR   PIR; G71323; G71323.
DR   AlphaFoldDB; O83453; -.
DR   SMR; O83453; -.
DR   IntAct; O83453; 3.
DR   STRING; 243276.TPANIC_0439; -.
DR   EnsemblBacteria; AAC65426; AAC65426; TP_0439.
DR   KEGG; tpa:TP_0439; -.
DR   eggNOG; COG0835; Bacteria.
DR   HOGENOM; CLU_048995_3_1_12; -.
DR   OMA; CVNIMSV; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   InterPro; IPR039315; CheW.
DR   InterPro; IPR036061; CheW-like_dom_sf.
DR   InterPro; IPR002545; CheW-lke_dom.
DR   PANTHER; PTHR22617; PTHR22617; 1.
DR   Pfam; PF01584; CheW; 1.
DR   SMART; SM00260; CheW; 1.
DR   SUPFAM; SSF50341; SSF50341; 1.
DR   PROSITE; PS50851; CHEW; 1.
PE   3: Inferred from homology;
KW   Chemotaxis; Cytoplasm; Reference proteome.
FT   CHAIN           1..170
FT                   /note="Chemotaxis protein CheW"
FT                   /id="PRO_0000198350"
FT   DOMAIN          20..164
FT                   /note="CheW-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00052"
SQ   SEQUENCE   170 AA;  19124 MW;  DE721FFE78BA9C4A CRC64;
     MYHGPTLHHR RVPMAVNDEQ FQLVTFQLGE ELYGIDIMGV KEIVKVQDVR PIPCAPAYVE
     GIFNLRSEII PIINLHKRFH LREATLESGD EYLGGFVILN VEDSKLGIII DRIARVIAVS
     QEDVQSPPQV ITGIGAEYIH GVVRQGTSYL IVLDIHKLFS SKELQKLANL