CHEY_PSEAE
ID CHEY_PSEAE Reviewed; 124 AA.
AC Q51455;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 123.
DE RecName: Full=Chemotaxis protein CheY;
GN Name=cheY; OrderedLocusNames=PA1456;
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=1560774; DOI=10.1111/j.1365-2958.1992.tb01490.x;
RA Starnbach M.N., Lory S.;
RT "The fliA (rpoF) gene of Pseudomonas aeruginosa encodes an alternative
RT sigma factor required for flagellin synthesis.";
RL Mol. Microbiol. 6:459-469(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 92-124.
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=7860605; DOI=10.1128/jb.177.4.948-952.1995;
RA Masduki A., Nakamura J., Ohga T., Umezaki R., Kato J., Ohtake H.;
RT "Isolation and characterization of chemotaxis mutants and genes of
RT Pseudomonas aeruginosa.";
RL J. Bacteriol. 177:948-952(1995).
CC -!- FUNCTION: Involved in the transmission of sensory signals from the
CC chemoreceptors to the flagellar motors. CheY is likely to be involved
CC in changing the direction of flagellar rotation.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
CC Note=Binds 1 Mg(2+) ion per subunit. {ECO:0000250};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
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DR EMBL; X61231; CAA43549.1; -; Genomic_DNA.
DR EMBL; AE004091; AAG04845.1; -; Genomic_DNA.
DR PIR; S20545; S20545.
DR RefSeq; NP_250147.1; NC_002516.2.
DR RefSeq; WP_003083073.1; NZ_QZGE01000005.1.
DR AlphaFoldDB; Q51455; -.
DR SMR; Q51455; -.
DR STRING; 287.DR97_567; -.
DR World-2DPAGE; 0008:Q51455; -.
DR PaxDb; Q51455; -.
DR PRIDE; Q51455; -.
DR DNASU; 882097; -.
DR EnsemblBacteria; AAG04845; AAG04845; PA1456.
DR GeneID; 57398831; -.
DR GeneID; 882097; -.
DR KEGG; pae:PA1456; -.
DR PATRIC; fig|208964.12.peg.1507; -.
DR PseudoCAP; PA1456; -.
DR HOGENOM; CLU_000445_69_12_6; -.
DR InParanoid; Q51455; -.
DR OMA; AAGAHEY; -.
DR PhylomeDB; Q51455; -.
DR BioCyc; PAER208964:G1FZ6-1482-MON; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0097588; P:archaeal or bacterial-type flagellum-dependent cell motility; IEA:UniProtKB-KW.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:1900192; P:positive regulation of single-species biofilm formation; IMP:PseudoCAP.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR Pfam; PF00072; Response_reg; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; SSF52172; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 3: Inferred from homology;
KW Chemotaxis; Cytoplasm; Flagellar rotation; Magnesium; Metal-binding;
KW Phosphoprotein; Reference proteome; Two-component regulatory system.
FT CHAIN 1..124
FT /note="Chemotaxis protein CheY"
FT /id="PRO_0000081054"
FT DOMAIN 2..119
FT /note="Response regulatory"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT BINDING 7
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000250"
FT BINDING 8
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000250"
FT BINDING 52
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000250"
FT BINDING 54
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000250"
FT MOD_RES 52
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 124 AA; 13902 MW; D75CFF1584295BFE CRC64;
MKILIVDDFS TMRRIIKNLL RDLGFTNTAE ADDGTTALPM LHSGNFDFLV TDWNMPGMTG
IDLLRAVRAD ERLKHLPVLM VTAEAKRDQI IEAAQAGVNG YVVKPFTAQV LKEKIEKIFE
RVNG
