ID   CHEY_TREPA              Reviewed;         144 AA.
AC   P96126;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   03-AUG-2022, entry version 131.
DE   RecName: Full=Chemotaxis protein CheY;
GN   Name=cheY; OrderedLocusNames=TP_0366;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9255518; DOI=10.3109/10425179709034046;
RA   Greene S.R., Stamm L.V., Hardham J.M., Young N.R., Frye J.G.;
RT   "Identification, sequences, and expression of Treponema pallidum chemotaxis
RT   genes.";
RL   DNA Seq. 7:267-284(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- FUNCTION: Involved in the transmission of sensory signals from the
CC       chemoreceptors to the flagellar motors. CheY seems to regulate the
CC       clockwise (CW) rotation (By similarity). {ECO:0000250}.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
CC       Note=Binds 1 Mg(2+) ion per subunit. {ECO:0000250};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- PTM: Phosphorylated by CheA. {ECO:0000250}.
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DR   EMBL; U61851; AAC45558.1; -; Genomic_DNA.
DR   EMBL; AE000520; AAC65351.1; -; Genomic_DNA.
DR   PIR; D71335; D71335.
DR   RefSeq; WP_010881814.1; NC_021490.2.
DR   AlphaFoldDB; P96126; -.
DR   SMR; P96126; -.
DR   STRING; 243276.TPANIC_0366; -.
DR   EnsemblBacteria; AAC65351; AAC65351; TP_0366.
DR   GeneID; 57878894; -.
DR   KEGG; tpa:TP_0366; -.
DR   eggNOG; COG2201; Bacteria.
DR   HOGENOM; CLU_000445_69_15_12; -.
DR   OMA; VMCTSVE; -.
DR   OrthoDB; 1630092at2; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0097588; P:archaeal or bacterial-type flagellum-dependent cell motility; IEA:UniProtKB-KW.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   Pfam; PF00072; Response_reg; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   3: Inferred from homology;
KW   Chemotaxis; Cytoplasm; Flagellar rotation; Magnesium; Metal-binding;
KW   Phosphoprotein; Reference proteome; Two-component regulatory system.
FT   CHAIN           1..144
FT                   /note="Chemotaxis protein CheY"
FT                   /id="PRO_0000081056"
FT   DOMAIN          26..143
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   BINDING         31
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000250"
FT   BINDING         32
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000250"
FT   BINDING         78
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000250"
FT   BINDING         80
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         78
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   144 AA;  15736 MW;  439BA06C877692AF CRC64;
     MISKQDFPTI NDRVPAGQKP NGAPYRVLVV DDSMFVSKQI GQILTSEGYE VADTAVDGVD
     GVEKYKAMSP GVDLVTMDIT MPKMDGITAL EKILEFDKNA KVVIISALGK EELVKKALLL
     GAKNYIVKPL DRKKVLERIA SVLK