CHEY_YERPE
ID CHEY_YERPE Reviewed; 129 AA.
AC Q8D0P1; Q0WGA3; Q8ZFL9;
DT 26-SEP-2003, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 03-AUG-2022, entry version 123.
DE RecName: Full=Chemotaxis protein CheY;
GN Name=cheY; OrderedLocusNames=YPO1680, y1842, YP_1810;
OS Yersinia pestis.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=632;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CO-92 / Biovar Orientalis;
RX PubMed=11586360; DOI=10.1038/35097083;
RA Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA Stevens K., Whitehead S., Barrell B.G.;
RT "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL Nature 413:523-527(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KIM10+ / Biovar Mediaevalis;
RX PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT "Genome sequence of Yersinia pestis KIM.";
RL J. Bacteriol. 184:4601-4611(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91001 / Biovar Mediaevalis;
RX PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA Wang J., Huang P., Yang R.;
RT "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT avirulent to humans.";
RL DNA Res. 11:179-197(2004).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Note=Binds 1 Mg(2+) ion per subunit.;
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- PTM: Phosphorylated by CheA or acetylated by acetyl-CoA synthetase,
CC depending on which acetate metabolism pathway is available.
CC {ECO:0000250}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAM85409.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=AAS62035.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AL590842; CAL20324.1; -; Genomic_DNA.
DR EMBL; AE009952; AAM85409.1; ALT_INIT; Genomic_DNA.
DR EMBL; AE017042; AAS62035.1; ALT_INIT; Genomic_DNA.
DR PIR; AI0204; AI0204.
DR RefSeq; WP_002210873.1; NZ_WUCM01000082.1.
DR RefSeq; YP_002346685.1; NC_003143.1.
DR AlphaFoldDB; Q8D0P1; -.
DR SMR; Q8D0P1; -.
DR IntAct; Q8D0P1; 5.
DR MINT; Q8D0P1; -.
DR STRING; 214092.YPO1680; -.
DR PaxDb; Q8D0P1; -.
DR DNASU; 1146789; -.
DR EnsemblBacteria; AAM85409; AAM85409; y1842.
DR EnsemblBacteria; AAS62035; AAS62035; YP_1810.
DR GeneID; 66841170; -.
DR KEGG; ype:YPO1680; -.
DR KEGG; ypk:y1842; -.
DR KEGG; ypm:YP_1810; -.
DR PATRIC; fig|214092.21.peg.2025; -.
DR eggNOG; COG0745; Bacteria.
DR HOGENOM; CLU_000445_69_12_6; -.
DR OMA; AAGAHEY; -.
DR Proteomes; UP000000815; Chromosome.
DR Proteomes; UP000001019; Chromosome.
DR Proteomes; UP000002490; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR Pfam; PF00072; Response_reg; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; SSF52172; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 3: Inferred from homology;
KW Acetylation; Cytoplasm; Magnesium; Metal-binding; Phosphoprotein;
KW Reference proteome; Two-component regulatory system.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250"
FT CHAIN 2..129
FT /note="Chemotaxis protein CheY"
FT /id="PRO_0000081048"
FT DOMAIN 7..124
FT /note="Response regulatory"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT BINDING 12
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000250"
FT BINDING 13
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000250"
FT BINDING 57
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000250"
FT BINDING 59
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000250"
FT MOD_RES 57
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT MOD_RES 92
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000250"
FT MOD_RES 109
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000250"
SQ SEQUENCE 129 AA; 14201 MW; BB4A99A9998DCD38 CRC64;
MADKNLRFLV VDDFSTMRRI VRNLLKELGF HNVEEAEDGV DALNKLRAGG FDFVVSDWNM
PNMDGLDLLK TIRTDGALAT LPVLMVTAEA KKENIIAAAQ AGASGYVVKP FTAATLEEKL
NKIFEKLGM
