CHEZ_SALTI
ID CHEZ_SALTI Reviewed; 214 AA.
AC Q8Z5V3; Q7CAL8;
DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 25-MAY-2022, entry version 101.
DE RecName: Full=Protein phosphatase CheZ;
DE EC=3.1.3.-;
DE AltName: Full=Chemotaxis protein CheZ;
GN Name=cheZ; OrderedLocusNames=STY2124, t0962;
OS Salmonella typhi.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=90370;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CT18;
RX PubMed=11677608; DOI=10.1038/35101607;
RA Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA Barrell B.G.;
RT "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT serovar Typhi CT18.";
RL Nature 413:848-852(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700931 / Ty2;
RX PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT CT18.";
RL J. Bacteriol. 185:2330-2337(2003).
CC -!- FUNCTION: Plays an important role in bacterial chemotaxis signal
CC transduction pathway by accelerating the dephosphorylation of
CC phosphorylated CheY (CheY-P). {ECO:0000250}.
CC -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the CheZ family. {ECO:0000305}.
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DR EMBL; AL513382; CAD05666.1; -; Genomic_DNA.
DR EMBL; AE014613; AAO68635.1; -; Genomic_DNA.
DR RefSeq; NP_456481.1; NC_003198.1.
DR RefSeq; WP_000983587.1; NZ_WSUR01000004.1.
DR AlphaFoldDB; Q8Z5V3; -.
DR SMR; Q8Z5V3; -.
DR STRING; 220341.16503161; -.
DR EnsemblBacteria; AAO68635; AAO68635; t0962.
DR KEGG; stt:t0962; -.
DR KEGG; sty:STY2124; -.
DR PATRIC; fig|220341.7.peg.2135; -.
DR eggNOG; COG3143; Bacteria.
DR HOGENOM; CLU_080718_1_0_6; -.
DR OMA; EGPQIHA; -.
DR Proteomes; UP000000541; Chromosome.
DR Proteomes; UP000002670; Chromosome.
DR GO; GO:0009288; C:bacterial-type flagellum; IEA:InterPro.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
DR GO; GO:0097588; P:archaeal or bacterial-type flagellum-dependent cell motility; IEA:UniProtKB-KW.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR GO; GO:0050920; P:regulation of chemotaxis; IEA:InterPro.
DR InterPro; IPR007439; Chemotax_Pase_CheZ.
DR Pfam; PF04344; CheZ; 1.
DR PIRSF; PIRSF002884; CheZ; 1.
PE 3: Inferred from homology;
KW Chemotaxis; Cytoplasm; Flagellar rotation; Hydrolase; Protein phosphatase.
FT CHAIN 1..214
FT /note="Protein phosphatase CheZ"
FT /id="PRO_0000410782"
FT REGION 176..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT SITE 147
FT /note="Enhances dephosphorylation of CheY-P"
FT /evidence="ECO:0000250"
SQ SEQUENCE 214 AA; 23934 MW; B4A34F2D54FC32FE CRC64;
MMQPSIKPAD EGSAGDIIAR IGSLTRMLRD SLRELGLDQA IAEAAEAIPD ARDRLDYVVQ
MTAQAAERAL NSVEASQPHQ DAMEKEAKAL TQRWDEWFDN PIELSDAREL VTDTRQFLRD
VPGHTSFTNA QLLDIMMAQD FQDLTGQVIK RMMDVIQEIE RQLLMVLLEN IPEQSARPKR
ENESLLNGPQ VDTSKAGVVA SQEQVDDLLD SLGF
