ID   CHEZ_VIBC3              Reviewed;         239 AA.
AC   A5F6J8;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Protein phosphatase CheZ;
DE            EC=3.1.3.-;
DE   AltName: Full=Chemotaxis protein CheZ;
GN   Name=cheZ; OrderedLocusNames=VC0395_A1652, VC395_2179;
OS   Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 /
OS   O395).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=345073;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39541 / Classical Ogawa 395 / O395;
RA   Heidelberg J.;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39541 / Classical Ogawa 395 / O395;
RX   PubMed=19115014; DOI=10.1371/journal.pone.0004053;
RA   Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J.,
RA   Wang W., Wang J., Qian W., Li D., Wang L.;
RT   "A recalibrated molecular clock and independent origins for the cholera
RT   pandemic clones.";
RL   PLoS ONE 3:E4053-E4053(2008).
CC   -!- FUNCTION: Plays an important role in bacterial chemotaxis signal
CC       transduction pathway by accelerating the dephosphorylation of
CC       phosphorylated CheY (CheY-P). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CheZ family. {ECO:0000305}.
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DR   EMBL; CP000627; ABQ20110.1; -; Genomic_DNA.
DR   EMBL; CP001235; ACP10171.1; -; Genomic_DNA.
DR   RefSeq; WP_000624259.1; NZ_JAACZH010000001.1.
DR   AlphaFoldDB; A5F6J8; -.
DR   SMR; A5F6J8; -.
DR   STRING; 345073.VC395_2179; -.
DR   EnsemblBacteria; ABQ20110; ABQ20110; VC0395_A1652.
DR   GeneID; 57740689; -.
DR   KEGG; vco:VC0395_A1652; -.
DR   KEGG; vcr:VC395_2179; -.
DR   PATRIC; fig|345073.21.peg.2106; -.
DR   eggNOG; COG3143; Bacteria.
DR   HOGENOM; CLU_080718_0_0_6; -.
DR   OMA; EGPQIHA; -.
DR   Proteomes; UP000000249; Chromosome 2.
DR   GO; GO:0009288; C:bacterial-type flagellum; IEA:InterPro.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
DR   GO; GO:0097588; P:archaeal or bacterial-type flagellum-dependent cell motility; IEA:UniProtKB-KW.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0050920; P:regulation of chemotaxis; IEA:InterPro.
DR   InterPro; IPR007439; Chemotax_Pase_CheZ.
DR   Pfam; PF04344; CheZ; 1.
DR   PIRSF; PIRSF002884; CheZ; 1.
PE   3: Inferred from homology;
KW   Chemotaxis; Cytoplasm; Flagellar rotation; Hydrolase; Protein phosphatase.
FT   CHAIN           1..239
FT                   /note="Protein phosphatase CheZ"
FT                   /id="PRO_0000410786"
FT   SITE            168
FT                   /note="Enhances dephosphorylation of CheY-P"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   239 AA;  27232 MW;  CDF6959677C90C65 CRC64;
     MISLEQAKEL VQLLEQGRQD DANRLFTYVY ESANNPMFKE IGMLTRDLHE ALKNFQIDER
     FSEIATDEIP DARERLHYVI QKTEVAANKT MDAVDRCMPI ADKLHESLLL IRPEWNGLMN
     GRIELMHFKS LCHRIDDLLS QVEGDSSELR GELTEILMAQ DFQDLTGQII KRVINLVNEV
     EKRLVEILTV FGAAQKEQKA DKATVASIEP EGPILNPHER IDAVSSQDEV DDLLSSLGF