ID   CHID1_DANRE             Reviewed;         391 AA.
AC   Q7SYK0;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Chitinase domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=chid1; ORFNames=zgc:66396;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=SJD;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted. Lysosome {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family. {ECO:0000305}.
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DR   EMBL; BC054696; AAH54696.1; -; mRNA.
DR   RefSeq; NP_956351.1; NM_200057.1.
DR   AlphaFoldDB; Q7SYK0; -.
DR   SMR; Q7SYK0; -.
DR   STRING; 7955.ENSDARP00000129029; -.
DR   PaxDb; Q7SYK0; -.
DR   GeneID; 337225; -.
DR   KEGG; dre:337225; -.
DR   CTD; 66005; -.
DR   ZFIN; ZDB-GENE-030131-9169; chid1.
DR   eggNOG; KOG2091; Eukaryota.
DR   InParanoid; Q7SYK0; -.
DR   OrthoDB; 1067925at2759; -.
DR   PhylomeDB; Q7SYK0; -.
DR   Reactome; R-DRE-114608; Platelet degranulation.
DR   PRO; PR:Q7SYK0; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IBA:GO_Central.
DR   GO; GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0008061; F:chitin binding; IEA:InterPro.
DR   GO; GO:0070492; F:oligosaccharide binding; IBA:GO_Central.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.10.50.10; -; 1.
DR   InterPro; IPR011583; Chitinase_II.
DR   InterPro; IPR029070; Chitinase_insertion_sf.
DR   InterPro; IPR001223; Glyco_hydro18_cat.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   Pfam; PF00704; Glyco_hydro_18; 1.
DR   SMART; SM00636; Glyco_18; 1.
DR   SUPFAM; SSF51445; SSF51445; 1.
DR   PROSITE; PS51910; GH18_2; 1.
PE   2: Evidence at transcript level;
KW   Lysosome; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..391
FT                   /note="Chitinase domain-containing protein 1"
FT                   /id="PRO_0000280612"
FT   DOMAIN          78..391
FT                   /note="GH18"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01258"
FT   REGION          27..46
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   391 AA;  44166 MW;  96D2D49E821DBDC5 CRC64;
     MRADWTFLLV CLLLPVVRST LSKTDAKKAS KVQEAESSVA ERPAQDRGLV VTDPQWRDIV
     REEKRFCHQC INTRQFKGAV LGYITPWNSH GYDIAKLFGP KLTSVSPVWL QLRRRGPESF
     HITGLHDHDP GWVKAVRKAN KKNKILPRLL FDGWSYQDYV SVLDSEDEME ELGREALEVA
     KAEGFDGYTL ELWSQLGGNK RKELVHLVTH LCETLNAGKL TCVLVIPPSV APGTGQPGMF
     GRDDFEKLAP VVDAFSLMTY DYSGPGRPGP SAPLPWVREC VLQLAPENQW RHKILLGVNM
     YGLDFSSHGG AEPLLGARCI ELLKEVKPKL QWDENTGEHF FNYKRNNGVK HVVYYPTLKF
     LQLRISLAAE LGTGISMWEL GQGLDYFYDL L