ID   CHID1_XENLA             Reviewed;         393 AA.
AC   Q68EX9;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Chitinase domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=chid1;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted. Lysosome {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family. {ECO:0000305}.
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DR   EMBL; BC080071; AAH80071.1; -; mRNA.
DR   RefSeq; NP_001087530.1; NM_001094061.1.
DR   RefSeq; XP_018112315.1; XM_018256826.1.
DR   AlphaFoldDB; Q68EX9; -.
DR   SMR; Q68EX9; -.
DR   MaxQB; Q68EX9; -.
DR   GeneID; 447354; -.
DR   KEGG; xla:447354; -.
DR   CTD; 447354; -.
DR   Xenbase; XB-GENE-5752812; chid1.L.
DR   OMA; YSINERI; -.
DR   OrthoDB; 1067925at2759; -.
DR   Proteomes; UP000186698; Chromosome 4L.
DR   Bgee; 447354; Expressed in muscle tissue and 19 other tissues.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0008061; F:chitin binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.10.50.10; -; 1.
DR   InterPro; IPR011583; Chitinase_II.
DR   InterPro; IPR029070; Chitinase_insertion_sf.
DR   InterPro; IPR001223; Glyco_hydro18_cat.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   Pfam; PF00704; Glyco_hydro_18; 1.
DR   SMART; SM00636; Glyco_18; 1.
DR   SUPFAM; SSF51445; SSF51445; 1.
DR   PROSITE; PS51910; GH18_2; 1.
PE   2: Evidence at transcript level;
KW   Lysosome; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..393
FT                   /note="Chitinase domain-containing protein 1"
FT                   /id="PRO_0000280613"
FT   DOMAIN          79..393
FT                   /note="GH18"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01258"
SQ   SEQUENCE   393 AA;  44310 MW;  EF50F9462B9C54BC CRC64;
     MRLLSTLLLV ATTYPLISAT LSKTDSKKAA SKAPETKTRL SDTSVQSRGL VSTDVKAKDI
     VLEHRSYCAK KLKERHVSAD VLGYVTPWNG HGYDIAKTFA AKFTLISSVW LQIRRKGREA
     YQVTGLHDVD QGWIKDIRKT SKSTQIVPRI LFDGWSYQDF ESVFNSEDEI EELAGAMVQT
     AKDEHFDGFV VEVWSQLGGQ KRQELVHLLI HIGEALHSAK LHFILVIPPA VAPGTDQLGM
     FGRKEFDQLA PVVDSFSLMT YDYSSPQRPG PNSPISWVQA CVQLLDPESK WRKKILLGLH
     FYGMDYSALG ATGEPILGNR YVEILKEHKP KLLWDQQIAE HYLEYKKNKG GKHAVFYPTL
     KSIQVRLDLA EELGTGIAIW ELGQGLDYFY DLL