ID   CHID1_XENTR             Reviewed;         394 AA.
AC   Q66IL0;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Chitinase domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=chid1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted. Lysosome {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family. {ECO:0000305}.
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DR   EMBL; BC081307; AAH81307.1; -; mRNA.
DR   RefSeq; NP_001008105.1; NM_001008104.1.
DR   RefSeq; XP_012816413.1; XM_012960959.2.
DR   RefSeq; XP_012816414.1; XM_012960960.2.
DR   AlphaFoldDB; Q66IL0; -.
DR   SMR; Q66IL0; -.
DR   STRING; 8364.ENSXETP00000042498; -.
DR   PaxDb; Q66IL0; -.
DR   PRIDE; Q66IL0; -.
DR   DNASU; 493467; -.
DR   Ensembl; ENSXETT00000041328; ENSXETP00000041328; ENSXETG00000019071.
DR   GeneID; 493467; -.
DR   KEGG; xtr:493467; -.
DR   CTD; 66005; -.
DR   Xenbase; XB-GENE-5752789; chid1.
DR   eggNOG; KOG2091; Eukaryota.
DR   HOGENOM; CLU_035132_2_0_1; -.
DR   InParanoid; Q66IL0; -.
DR   OMA; IKHSSIC; -.
DR   OrthoDB; 1067925at2759; -.
DR   PhylomeDB; Q66IL0; -.
DR   TreeFam; TF319271; -.
DR   Reactome; R-XTR-114608; Platelet degranulation.
DR   Proteomes; UP000008143; Chromosome 4.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000019071; Expressed in testis and 12 other tissues.
DR   GO; GO:0005576; C:extracellular region; IBA:GO_Central.
DR   GO; GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0008061; F:chitin binding; IEA:InterPro.
DR   GO; GO:0070492; F:oligosaccharide binding; IBA:GO_Central.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.10.50.10; -; 1.
DR   InterPro; IPR011583; Chitinase_II.
DR   InterPro; IPR029070; Chitinase_insertion_sf.
DR   InterPro; IPR001223; Glyco_hydro18_cat.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   Pfam; PF00704; Glyco_hydro_18; 1.
DR   SMART; SM00636; Glyco_18; 1.
DR   SUPFAM; SSF51445; SSF51445; 1.
DR   PROSITE; PS51910; GH18_2; 1.
PE   2: Evidence at transcript level;
KW   Lysosome; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..394
FT                   /note="Chitinase domain-containing protein 1"
FT                   /id="PRO_0000280614"
FT   DOMAIN          80..394
FT                   /note="GH18"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01258"
SQ   SEQUENCE   394 AA;  44529 MW;  B9273360A8D2426E CRC64;
     MRLLSTLLFL VAATCPLIHA TLSKTDSKKA ASKAPETKTR LSDTLVQTRG LVSTDVKAKD
     IVLEHRSYCA KKLKERHVSA DVLGYVTPWN GHGYDIAKTF AAKFTLISPV WLQIKRKGKE
     AYHITGLHDV DQGWIKDIRK TSKSTQIVPR ILFDGWSYQD FESVFSSEDE IEELAGAMVQ
     TAKDERFDGF VVEVWSQLGG QKRQELVHLL THIGEALRLA KLRFILVIPP ALAPGTDHLG
     MFGRKEFDQL APVVDSFSLM TYDYSSPQRP GPNSPITWVQ ACIQLLDPES KWRKKILLGL
     HFYGMDYSAL GASGEPILGN RYIEILKEHK PKLLWDQQIA EHYLEYKKNK GGKHAVFFPT
     LKSIQVRLDL AEELGTGISI WELGQGLDYF YDLL