CHLP_ORYSJ
ID CHLP_ORYSJ Reviewed; 463 AA.
AC Q6Z2T6; Q0DXL8;
DT 13-OCT-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 125.
DE RecName: Full=Geranylgeranyl diphosphate reductase, chloroplastic;
DE EC=1.3.1.83;
DE AltName: Full=Geranylgeranyl reductase;
DE Flags: Precursor;
GN Name=CHLP; OrderedLocusNames=Os02g0744900, LOC_Os02g51080;
GN ORFNames=OJ1118_G04.11, OJ1734_E02.38, OsJ_08361;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
CC -!- FUNCTION: Catalyzes the reduction of geranylgeranyl diphosphate to
CC phytyl diphosphate, providing phytol for both tocopherol and
CC chlorophyll synthesis. {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3 NADP(+) + phytyl diphosphate = geranylgeranyl diphosphate +
CC 3 H(+) + 3 NADPH; Xref=Rhea:RHEA:26229, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57533, ChEBI:CHEBI:57783, ChEBI:CHEBI:58349,
CC ChEBI:CHEBI:75434; EC=1.3.1.83;
CC -!- PATHWAY: Porphyrin-containing compound metabolism; chlorophyll
CC biosynthesis.
CC -!- PATHWAY: Cofactor biosynthesis; tocopherol biosynthesis.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the geranylgeranyl reductase family. ChlP
CC subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAF10020.2; Type=Erroneous initiation; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP004114; BAD15541.1; -; Genomic_DNA.
DR EMBL; AP005297; BAD16125.1; -; Genomic_DNA.
DR EMBL; AP008208; BAF10020.2; ALT_INIT; Genomic_DNA.
DR EMBL; AP014958; BAS80895.1; -; Genomic_DNA.
DR EMBL; CM000139; EAZ24599.1; -; Genomic_DNA.
DR EMBL; AK061968; BAG88184.1; -; mRNA.
DR RefSeq; XP_015627112.1; XM_015771626.1.
DR AlphaFoldDB; Q6Z2T6; -.
DR SMR; Q6Z2T6; -.
DR BioGRID; 799748; 1.
DR STRING; 4530.OS02T0744900-01; -.
DR PaxDb; Q6Z2T6; -.
DR PRIDE; Q6Z2T6; -.
DR EnsemblPlants; Os02t0744900-01; Os02t0744900-01; Os02g0744900.
DR GeneID; 4330711; -.
DR Gramene; Os02t0744900-01; Os02t0744900-01; Os02g0744900.
DR KEGG; osa:4330711; -.
DR eggNOG; ENOG502QQWY; Eukaryota.
DR HOGENOM; CLU_024648_3_1_1; -.
DR InParanoid; Q6Z2T6; -.
DR OMA; GMCRREV; -.
DR OrthoDB; 894979at2759; -.
DR BRENDA; 1.3.1.83; 8948.
DR PlantReactome; R-OSA-1119602; Phytyl-PP biosynthesis.
DR PlantReactome; R-OSA-1119605; Chlorophyll a biosynthesis II.
DR UniPathway; UPA00160; -.
DR UniPathway; UPA00668; -.
DR Proteomes; UP000000763; Chromosome 2.
DR Proteomes; UP000007752; Chromosome 2.
DR Proteomes; UP000059680; Chromosome 2.
DR ExpressionAtlas; Q6Z2T6; baseline and differential.
DR Genevisible; Q6Z2T6; OS.
DR GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0102067; F:geranylgeranyl diphosphate reductase activity; IEA:UniProtKB-EC.
DR GO; GO:0045550; F:geranylgeranyl reductase activity; IBA:GO_Central.
DR GO; GO:0015995; P:chlorophyll biosynthetic process; IBA:GO_Central.
DR GO; GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
DR GO; GO:0010189; P:vitamin E biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.50.50.60; -; 1.
DR InterPro; IPR010253; BchP_ChlP_pln/prok.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR011777; Geranylgeranyl_Rdtase_fam.
DR InterPro; IPR011774; Geranylgeranyl_Rdtase_pln/cyn.
DR Pfam; PF01494; FAD_binding_3; 1.
DR SUPFAM; SSF51905; SSF51905; 1.
DR TIGRFAMs; TIGR02023; BchP-ChlP; 1.
DR TIGRFAMs; TIGR02028; ChlP; 1.
DR TIGRFAMs; TIGR02032; GG-red-SF; 1.
PE 2: Evidence at transcript level;
KW Chlorophyll biosynthesis; Chloroplast; NADP; Oxidoreductase;
KW Photosynthesis; Plastid; Reference proteome; Transit peptide.
FT TRANSIT 1..37
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 38..463
FT /note="Geranylgeranyl diphosphate reductase, chloroplastic"
FT /id="PRO_0000386543"
SQ SEQUENCE 463 AA; 50587 MW; 27FBA8B90C48324A CRC64;
MTSLSSSAAA ARATFVMPSS VRGGMSRGRR MARLVTRAAA SSPKLPSGRR LRVAVVGGGP
AGGAAAEALA KGGVETVLIE RKLDNCKPCG GAIPLCMVSE FDLPLDLVDR KVRKMKMISP
SNVAVDIGGT LAPHEYIGMV RREVLDAYLR SRAEGAGAEV VNGLFLRYEA PKEPNGSYVV
HYNHYDSSNG KAGGEKRTFE VDAIVGADGA NSRVAKDMGA GDYEYAIAFQ ERVKIPDDKM
KYYEERAEMY VGDDVSPDFY GWVFPKCDHV AVGTGTVTHK PDIKKFQAAT RLRAKDRIEG
GKIIRVEAHP IPEHPRPKRV AGRVTLVGDA AGYVTKCSGE GIYFAAKSGR MCAEAIVAGS
ANGTRMVEES DLRRYLAEFD RLYWPTYKVL DVLQKVFYRS NAAREAFVEM CADDYVQRMT
FDSYLYKRVV PGNPLDDIKL AVNTIGSLVR ATALRREMEK VTL
