CHR10_ARATH
ID CHR10_ARATH Reviewed; 877 AA.
AC F4IV45;
DT 09-DEC-2015, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 68.
DE RecName: Full=Probable helicase CHR10 {ECO:0000305};
DE EC=3.6.4.- {ECO:0000305};
DE AltName: Full=Protein ALTERED SEED GERMINATION 3 {ECO:0000305};
DE AltName: Full=Protein CHROMATIN REMODELING 10 {ECO:0000305};
GN Name=CHR10 {ECO:0000305}; Synonyms=ASG3 {ECO:0000305};
GN OrderedLocusNames=At2g44980 {ECO:0000312|Araport:AT2G44980};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- FUNCTION: Probable helicase-like transcription factor.
CC {ECO:0000250|UniProtKB:Q9LHE4}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9ZUL5}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences. {ECO:0000305};
CC Name=1;
CC IsoId=F4IV45-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the SNF2/RAD54 helicase family. {ECO:0000305}.
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DR EMBL; CP002685; AEC10493.1; -; Genomic_DNA.
DR RefSeq; NP_973689.2; NM_201960.3. [F4IV45-1]
DR AlphaFoldDB; F4IV45; -.
DR SMR; F4IV45; -.
DR STRING; 3702.AT2G44980.2; -.
DR PaxDb; F4IV45; -.
DR PRIDE; F4IV45; -.
DR EnsemblPlants; AT2G44980.2; AT2G44980.2; AT2G44980. [F4IV45-1]
DR GeneID; 819106; -.
DR Gramene; AT2G44980.2; AT2G44980.2; AT2G44980. [F4IV45-1]
DR KEGG; ath:AT2G44980; -.
DR Araport; AT2G44980; -.
DR TAIR; locus:2054955; AT2G44980.
DR eggNOG; KOG0385; Eukaryota.
DR InParanoid; F4IV45; -.
DR OrthoDB; 61251at2759; -.
DR PhylomeDB; F4IV45; -.
DR PRO; PR:F4IV45; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; F4IV45; baseline and differential.
DR GO; GO:0000785; C:chromatin; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IBA:GO_Central.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IBA:GO_Central.
DR GO; GO:0003682; F:chromatin binding; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0042393; F:histone binding; IBA:GO_Central.
DR GO; GO:0006338; P:chromatin remodeling; IBA:GO_Central.
DR Gene3D; 3.40.220.10; -; 1.
DR Gene3D; 3.40.50.10810; -; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR043472; Macro_dom-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR000330; SNF2_N.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; SSF52540; 2.
DR SUPFAM; SSF52949; SSF52949; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW Alternative splicing; ATP-binding; Chromatin regulator; DNA-binding;
KW Helicase; Hydrolase; Nucleotide-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..877
FT /note="Probable helicase CHR10"
FT /id="PRO_0000435119"
FT DOMAIN 64..239
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
FT DOMAIN 381..548
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00542"
FT BINDING 77..84
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
SQ SEQUENCE 877 AA; 98867 MW; 3658F6736D9BC03D CRC64;
MSKESSPPKV PSTTMEYERR LEAAAEIILE KEAKFSNTPP DCSEFGVTAT LKPHQVEGVS
WLIQKYLLGV NVVLELDQMG LGKTLQAISF LSYLKFRQGL PGPFLVLCPL SVTDGWVSEI
NRFTPNLEVL RYVGDKYCRL DMRKSMYDHV KKSSKGHFLP FDVLLTTYDI ALVDQDFLSQ
IPWQYAIIDE AQRLKNPNSV LYNVLLEQFL IPRRLLITGT PIQNNLTELW ALMHFCMPLV
FGTLDQFLSA FKETGDGLSG LDVSNDKETY KSLKFILGAF MLRRTKSLLI ESGNLVLPPL
TELTVMVPLV SLQKKIYTSI LRKELPGLLE LSSGGSNHTS LQNIVIQLRK ACSHPYLFPG
IEPEPFEEGE HLVQASGKLL VLDQLLKRLH DSGHRVLLFS QMTSTLDILQ DFMELRRYSY
ERLDGSVRAE ERFAAIKNFS AKTERGLDSE VDGSNAFVFM ISTRAGGVGL NLVAADTVIF
YEQDWNPQVD KQALQRAHRI GQISHVLSIN LVTEHSVEEV ILRRAERKLQ LSHNVVGDNM
EEKEEDGGDL RSLVFGLQRF DPEEIHNEES DNLKMVEISS LAEKVVAIRQ NVEPDKEERR
FEINSSDTLL GNTSSASLDS ELDEASYLSW VEKLKEAARS SKDEKIIELG NRKNLSEERN
LRIEAARKKA EEKKLATWGA HGYQSLSVEE PILPDDVDSS SDAGSVNFVF GDCTNPSTVS
HEPAIIFSCV DDSGNWGRGG MFDALSKLSN TVPTAYHRAS EFKDLHLGDL HLIKIDDNDD
QQNTQASKPL WVAVAVTQSY NSRRKVPRSS ISIPDLESCL AKASFSASQK SASLHMPRIG
YQDGSDRSQW YTVERLLRKY SSIFTVKIFV YYYRRSP
