CHR3_SCHPO
ID CHR3_SCHPO Reviewed; 932 AA.
AC Q09897;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1996, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Chitin synthase regulatory factor 3;
DE AltName: Full=Chs four homolog 1;
GN Name=chr3; Synonyms=cfh1; ORFNames=SPAC24B11.10c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP IDENTIFICATION, AND POSSIBLE FUNCTION.
RX PubMed=15449309; DOI=10.1002/yea.1145;
RA Matsuo Y., Matsuura Y., Tanaka K., Matsuda H., Kawamukai M.;
RT "Chr4, a Schizosaccharomyces pombe homologue of the Saccharomyces
RT cerevisiae Chs4p/Skt5p protein, is related to septum formation and is
RT required for the proper localization of Chs2.";
RL Yeast 21:1005-1019(2004).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-393, AND IDENTIFICATION BY
RP MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
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DR EMBL; CU329670; CAA91775.1; -; Genomic_DNA.
DR PIR; T38337; S62555.
DR RefSeq; NP_592847.1; NM_001018248.2.
DR AlphaFoldDB; Q09897; -.
DR SMR; Q09897; -.
DR BioGRID; 278104; 8.
DR STRING; 4896.SPAC24B11.10c.1; -.
DR iPTMnet; Q09897; -.
DR MaxQB; Q09897; -.
DR PaxDb; Q09897; -.
DR PRIDE; Q09897; -.
DR EnsemblFungi; SPAC24B11.10c.1; SPAC24B11.10c.1:pep; SPAC24B11.10c.
DR GeneID; 2541607; -.
DR KEGG; spo:SPAC24B11.10c; -.
DR PomBase; SPAC24B11.10c; -.
DR VEuPathDB; FungiDB:SPAC24B11.10c; -.
DR eggNOG; KOG1550; Eukaryota.
DR HOGENOM; CLU_016507_0_0_1; -.
DR InParanoid; Q09897; -.
DR OMA; QCKLGEC; -.
DR PRO; PR:Q09897; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0032153; C:cell division site; HDA:PomBase.
DR GO; GO:0051286; C:cell tip; HDA:PomBase.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0044732; C:mitotic spindle pole body; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR Gene3D; 1.25.40.10; -; 2.
DR InterPro; IPR006597; Sel1-like.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR Pfam; PF08238; Sel1; 6.
DR SMART; SM00671; SEL1; 7.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome; Repeat.
FT CHAIN 1..932
FT /note="Chitin synthase regulatory factor 3"
FT /id="PRO_0000076206"
FT REPEAT 638..674
FT /note="Sel1-like 1"
FT REPEAT 675..710
FT /note="Sel1-like 2"
FT REPEAT 711..747
FT /note="Sel1-like 3"
FT REPEAT 751..788
FT /note="Sel1-like 4"
FT REPEAT 789..825
FT /note="Sel1-like 5"
FT REPEAT 826..863
FT /note="Sel1-like 6"
FT REPEAT 864..899
FT /note="Sel1-like 7"
FT REGION 1..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 264..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 374..406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 905..932
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..53
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..358
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 382..406
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 393
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 932 AA; 103184 MW; 86C1F6EFF94BB452 CRC64;
MKDSHSSRRK YEKEKLVFAT NNGKRTEGTP AFLKSGNTAS SSSPTLQFRP TSRYPTLSHE
PVYTNVLDLS SRIDANRASI MSATMGTPPS ALKFSKKKIS RPVVSEDTFK DKLPRATIPV
KPEPQPQYKI PAAPAPTSKR VVNRGLKLNT NLRQASPILP SPSLKLDRQD APIQINHEQK
EDFLVSIPRP TPMTNLDDGK DEIGQPDPHR KYMAPPRVNS ISRVQRRMSY IPYGGFDDFL
DNYYKDDDTV LEDNQLKSNS RIETLEEEDG AESDSITNTV SNASSDAEPA HRHLGPVYEN
SGHLPSKSHF SSTDSNTDSF GLESDERSLP SVSNDLKSSE TLKNPRNDDL LTLQQPPRYP
HSQMVMLPAR SPVEVPAPTF DRRNVSRNSN NNSPEGYDNN RTNPTVNNLP SYPTNLARPK
AIKPMPTSIH GQTSPLSPIP PVHTTHGLVS DIRPLPSVSS PIMRADSTPI SHNLAVTPSF
SPIPQQSNKS IGNHKNTSVA NVSSKVANSK FERNISMMSN SNASSPAIFE VGAEAKEKTK
DAIPCHPDDK LMIPSPKIVT HGDAMQEEQR LRQKSQITPD DEVELAKVYL NALETLENKP
SLAPDQASYN TRINVYRTRA VELLKKNAYP SKTQNTVPEA LFLIGQFHSQ GVLGFRRDLG
KAFELYSLAA KKGHPLSNYR VAVCLQTGTG VKPDTSKCVA IYKKAAEMDV VEAMFRIALI
YLNGLLGQKR NISLGVQWLE RACKSKGPES VRAMYELAKI YEQPDRYGVS ATPERKFELY
KQSAVYGYAA AQCKLGECYE HGLLGCLAEP RRSIFWYTRA AEQDYGEAEL GLSGWYLTGS
EGILPKNGEE ALLWAHKAAC KGLAKAQYAV GFMMEQGIGV AADPSSAHNW YIRAAKQGFP
KAKKRLEEQA LSSKQTHSKA PKKKQQEQCV VM
