ID   CHRA_PSEAI              Reviewed;         416 AA.
AC   P14285;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1990, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Chromate transport protein {ECO:0000305};
GN   Name=chrA {ECO:0000303|PubMed:2152903};
OS   Pseudomonas aeruginosa.
OG   Plasmid pUM505.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, AND INDUCTION.
RX   PubMed=2152903; DOI=10.1128/jb.172.1.287-291.1990;
RA   Cervantes C., Ohtake H., Chu L., Misra T.K., Silver S.;
RT   "Cloning, nucleotide sequence, and expression of the chromate resistance
RT   determinant of Pseudomonas aeruginosa plasmid pUM505.";
RL   J. Bacteriol. 172:287-291(1990).
CC   -!- FUNCTION: This protein reduces chromate accumulation and is essential
CC       for chromate resistance. {ECO:0000269|PubMed:2152903}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305|PubMed:2152903};
CC       Multi-pass membrane protein {ECO:0000255}.
CC   -!- INDUCTION: By chromate. {ECO:0000269|PubMed:2152903}.
CC   -!- SIMILARITY: Belongs to the chromate ion transporter (CHR) (TC 2.A.51)
CC       family. {ECO:0000305}.
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DR   EMBL; M29034; AAA88432.1; -; Genomic_DNA.
DR   RefSeq; WP_003117270.1; NZ_VKLB01000041.1.
DR   RefSeq; YP_004928064.1; NC_016138.1.
DR   AlphaFoldDB; P14285; -.
DR   TCDB; 2.A.51.1.3; the chromate ion transporter (chr) family.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015109; F:chromate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0046687; P:response to chromate; IEA:UniProtKB-KW.
DR   InterPro; IPR014047; Chr_Tranpt_l_chain.
DR   InterPro; IPR003370; Chromate_transpt.
DR   Pfam; PF02417; Chromate_transp; 2.
DR   PIRSF; PIRSF004810; ChrA; 1.
DR   TIGRFAMs; TIGR00937; 2A51; 1.
PE   2: Evidence at transcript level;
KW   Cell inner membrane; Cell membrane; Chromate resistance; Membrane; Plasmid;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..416
FT                   /note="Chromate transport protein"
FT                   /id="PRO_0000089653"
FT   TRANSMEM        99..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        128..148
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        160..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        181..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        204..224
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        237..257
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        283..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        308..328
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        341..361
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        371..391
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        395..415
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   416 AA;  44060 MW;  19F46F4D3B0D2479 CRC64;
     MSVANEESYR PSKATDATTE AVPPPMSYPQ LFARFLKFGL LAWGGPVAQI DMLRRELVDE
     ERWISSKRFN KLLAVMQVLP GPEAHEICVH LGIRAKGRLG GVLAGLGFML PGFLLMFALS
     WLYFQIEFVG TALGAAFLGV QAAVIALIVR AVHRIGEHIL LDRWLWVIAI VCALAAIGRV
     DFWITLPAGG LVYALLVLNH RASALLVTLA AVALAAAVAL WAAPTAKLVE AVVQGQASVL
     LIFASGLKAG LLTFGGAYTA IPFVRNDAVG RGWMTDGQFL DGLALSGVLP APLIIFATFV
     GYVAGGPIGA VAMTVGVFLP AFAFSLIFYD RLEAVVENKR LHAFLDGVAA GVVGLIGATT
     IDLAQVTAER VPSLTVGMSI FAAGLAFLYA WKNKLNVVVV ILAAGLAGWL VFPNQG