ID   CHS1_TUBUN              Reviewed;         189 AA.
AC   P55003;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Chitin synthase 1;
DE            EC=2.4.1.16;
DE   AltName: Full=Chitin-UDP acetyl-glucosaminyl transferase 1;
DE   Flags: Fragment;
GN   Name=CHS1;
OS   Tuber uncinatum (Burgundy truffle).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Pezizomycetes;
OC   Pezizales; Tuberaceae; Tuber.
OX   NCBI_TaxID=36049;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7944356; DOI=10.1128/aem.60.9.3105-3111.1994;
RA   Mehmann B., Brunner I., Braus G.H.;
RT   "Nucleotide sequence variation of chitin synthase genes among
RT   ectomycorrhizal fungi and its potential use in taxonomy.";
RL   Appl. Environ. Microbiol. 60:3105-3111(1994).
CC   -!- FUNCTION: Polymerizes chitin, a structural polymer of the cell wall and
CC       septum, by transferring the sugar moiety of UDP-GlcNAc to the non-
CC       reducing end of the growing chitin polymer. {ECO:0000305}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[(1->4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-
CC         D-glucosamine = [(1->4)-N-acetyl-beta-D-glucosaminyl](n+1) + H(+) +
CC         UDP; Xref=Rhea:RHEA:16637, Rhea:RHEA-COMP:9593, Rhea:RHEA-COMP:9595,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:17029, ChEBI:CHEBI:57705,
CC         ChEBI:CHEBI:58223; EC=2.4.1.16;
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the chitin synthase family. {ECO:0000305}.
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DR   EMBL; X78101; CAA54994.1; -; Genomic_DNA.
DR   AlphaFoldDB; P55003; -.
DR   CAZy; GT2; Glycosyltransferase Family 2.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004100; F:chitin synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR   GO; GO:0006031; P:chitin biosynthetic process; IEA:InterPro.
DR   InterPro; IPR004835; Chitin_synth.
DR   InterPro; IPR004834; Chitin_synth_fun.
DR   PANTHER; PTHR22914; PTHR22914; 1.
DR   Pfam; PF01644; Chitin_synth_1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Cell wall biogenesis/degradation; Glycosyltransferase;
KW   Membrane; Transferase; Transmembrane.
FT   CHAIN           <1..>189
FT                   /note="Chitin synthase 1"
FT                   /id="PRO_0000193718"
FT   NON_TER         1
FT   NON_TER         189
SQ   SEQUENCE   189 AA;  21187 MW;  940F6C0ABA7422C9 CRC64;
     EMNFTRTMHG VMRNIAHFCS RSKSRVWGKD GWQKIVVCIV ADGRKKVHPR VLDAFPAMGV
     YQAGIAKNSI NGREVKAHVY EYTTQVSLDS DLKFKGAEKG IVPVQMIFCL KELNAKKLNS
     HRCIFQRFWS TLNPNVCILL DVGTRPGHDS LYHLWKAFDT DSNVGGACGE IKAMKGKGWM
     GLFNPLVAS