CHS7_ASPCL
ID CHS7_ASPCL Reviewed; 332 AA.
AC A1CPR8;
DT 20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 1.
DT 25-MAY-2022, entry version 64.
DE RecName: Full=Chitin synthase export chaperone;
GN Name=chs7; ORFNames=ACLA_023530;
OS Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 /
OS NRRL 1 / QM 1276 / 107).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=344612;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1;
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC -!- FUNCTION: Chaperone required for the export of the chitin synthase chs3
CC from the endoplasmic reticulum. {ECO:0000250}.
CC -!- SUBUNIT: Interacts with chs3. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC Multi-pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the CHS7 family. {ECO:0000305}.
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DR EMBL; DS027059; EAW07639.1; -; Genomic_DNA.
DR RefSeq; XP_001269065.1; XM_001269064.1.
DR AlphaFoldDB; A1CPR8; -.
DR STRING; 5057.CADACLAP00002917; -.
DR EnsemblFungi; EAW07639; EAW07639; ACLA_023530.
DR GeneID; 4701778; -.
DR KEGG; act:ACLA_023530; -.
DR VEuPathDB; FungiDB:ACLA_023530; -.
DR eggNOG; ENOG502QRVH; Eukaryota.
DR HOGENOM; CLU_050424_1_1_1; -.
DR OMA; SKATVWE; -.
DR OrthoDB; 1163040at2759; -.
DR Proteomes; UP000006701; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR022057; Chs7.
DR PANTHER; PTHR35329; PTHR35329; 1.
DR Pfam; PF12271; Chs7; 1.
PE 3: Inferred from homology;
KW Cell wall biogenesis/degradation; Endoplasmic reticulum; Membrane;
KW Protein transport; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..332
FT /note="Chitin synthase export chaperone"
FT /id="PRO_0000280568"
FT TRANSMEM 49..69
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 85..105
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 123..143
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 151..171
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 185..205
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 220..240
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 250..270
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 332 AA; 36847 MW; 25911AB8B49E93E2 CRC64;
MGFGDFDSIC AKTALPLCSL VGPSSSSISG STGIISNCYA RNVELANTII FEGAASFVHI
IALAMTVIMI LHVRSKFTAV GRKEIITFFY IYMALTICSL VIDAGVVPPR SGPFPYFVAA
QNGLASALCT CLLVNGFVGF QLYEDGTFLS VWLLRLTSAV MFVVSFLISI LTFKSWGGMS
PTNTIGLFVV LYILNALCIA IYLVMQLLLV MNTLEDRWPL GHIAFGVIVF ICGQVLLYAF
SDTICDNVQH YLDGLFFATF CNLLAVMMVY KFWDYITKED LEFSVGIKPN TWEVKELLPE
EDRRTTAYQD SHSEYAGSMY HHRASTYGNQ NY
