ID   CHS7_CANAL              Reviewed;         310 AA.
AC   Q5AA40; A0A1D8PDP7;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Chitin synthase export chaperone;
GN   Name=CHS7; OrderedLocusNames=CAALFM_C106010WA;
GN   ORFNames=CaO19.2444, CaO19.9980;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- FUNCTION: Chaperone required for the export of the chitin synthase CHS3
CC       from the endoplasmic reticulum. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with CHS3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CHS7 family. {ECO:0000305}.
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DR   EMBL; CP017623; AOW26265.1; -; Genomic_DNA.
DR   RefSeq; XP_718467.1; XM_713374.1.
DR   AlphaFoldDB; Q5AA40; -.
DR   SMR; Q5AA40; -.
DR   STRING; 237561.Q5AA40; -.
DR   PRIDE; Q5AA40; -.
DR   GeneID; 3639869; -.
DR   KEGG; cal:CAALFM_C106010WA; -.
DR   CGD; CAL0000175393; CHS7.
DR   VEuPathDB; FungiDB:C1_06010W_A; -.
DR   eggNOG; ENOG502QRVH; Eukaryota.
DR   HOGENOM; CLU_050424_1_1_1; -.
DR   InParanoid; Q5AA40; -.
DR   OMA; SKATVWE; -.
DR   OrthoDB; 1163040at2759; -.
DR   PHI-base; PHI:484; -.
DR   PRO; PR:Q5AA40; -.
DR   Proteomes; UP000000559; Chromosome 1.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR   GO; GO:0006038; P:cell wall chitin biosynthetic process; IMP:CGD.
DR   GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR   GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; ISS:CGD.
DR   GO; GO:0030447; P:filamentous growth; IMP:CGD.
DR   GO; GO:0044182; P:filamentous growth of a population of unicellular organisms; IMP:CGD.
DR   GO; GO:0000128; P:flocculation; IMP:CGD.
DR   GO; GO:0034221; P:fungal-type cell wall chitin biosynthetic process; IBA:GO_Central.
DR   GO; GO:1900429; P:negative regulation of filamentous growth of a population of unicellular organisms; IMP:CGD.
DR   GO; GO:0060257; P:negative regulation of flocculation; IMP:CGD.
DR   GO; GO:0006457; P:protein folding; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0051223; P:regulation of protein transport; ISS:CGD.
DR   InterPro; IPR022057; Chs7.
DR   PANTHER; PTHR35329; PTHR35329; 1.
DR   Pfam; PF12271; Chs7; 1.
PE   3: Inferred from homology;
KW   Cell wall biogenesis/degradation; Endoplasmic reticulum; Membrane;
KW   Protein transport; Reference proteome; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..310
FT                   /note="Chitin synthase export chaperone"
FT                   /id="PRO_0000280571"
FT   TRANSMEM        50..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        86..106
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        114..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        151..171
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        194..214
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        221..241
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        257..277
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   310 AA;  34709 MW;  CDB07F2D43991D18 CRC64;
     MSFGSFDHIC NKTALPLCSV VGAVNQSAFF QRGIVPDCYA RSVELANTMI FQIGNAFVHF
     GGLIILLIII FNVRAKYTAI GRKEMLFFLY LAIGLIVSSL IVDCGVSPPS STSYAYFVAV
     QIGLSSALCI CLLYNGFLCF QFWEDGTSRS MWILRVGCFA WFAVNFIVCI ITFKHWDTAL
     DYRKTTTLFI FAYVLNAVIL AVYVVSQIIL VVFALESYWS LGAILLGVFF FVAGQVLTYV
     FSDKICRGAS HYVDGLFFGS ACNVFTFMMI YKFWDMITSD DLEFSVANVE QPINEFGVGA
     DDEKRSSMFF