ID   CHS7_SOYBN              Reviewed;         389 AA.
AC   P30081;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   25-MAY-2022, entry version 116.
DE   RecName: Full=Chalcone synthase 7;
DE            EC=2.3.1.74;
DE   AltName: Full=Naringenin-chalcone synthase 7;
GN   Name=CHS7;
OS   Glycine max (Soybean) (Glycine hispida).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC   Glycine subgen. Soja.
OX   NCBI_TaxID=3847;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=cv. Williams;
RX   PubMed=8108501; DOI=10.1104/pp.102.1.321;
RA   Akada S., Kung S.D., Dube S.K.;
RT   "Nucleotide sequence and putative regulatory elements of a nodule-
RT   development-specific member of the soybean (Glycine max) chalcone synthase
RT   multigene family, Gmchs 7.";
RL   Plant Physiol. 102:321-323(1993).
CC   -!- FUNCTION: The primary product of this enzyme is 4,2',4',6'-
CC       tetrahydroxychalcone (also termed naringenin-chalcone or chalcone)
CC       which can under specific conditions spontaneously isomerize into
CC       naringenin.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=4-coumaroyl-CoA + 2 H(+) + 3 malonyl-CoA = 2',4,4',6'-
CC         tetrahydroxychalcone + 3 CO2 + 4 CoA; Xref=Rhea:RHEA:11128,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:57287,
CC         ChEBI:CHEBI:57355, ChEBI:CHEBI:57384, ChEBI:CHEBI:77645; EC=2.3.1.74;
CC         Evidence={ECO:0000255|PROSITE-ProRule:PRU10023};
CC   -!- PATHWAY: Secondary metabolite biosynthesis; flavonoid biosynthesis.
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC       synthases family. {ECO:0000305}.
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DR   EMBL; M98871; AAA33950.1; -; Genomic_DNA.
DR   PIR; JQ1071; JQ1071.
DR   PIR; JQ2250; JQ2250.
DR   RefSeq; XP_003517529.1; XM_003517481.3.
DR   AlphaFoldDB; P30081; -.
DR   SMR; P30081; -.
DR   STRING; 3847.GLYMA01G43880.1; -.
DR   PRIDE; P30081; -.
DR   EnsemblPlants; KRH77699; KRH77699; GLYMA_01G228700.
DR   Gramene; KRH77699; KRH77699; GLYMA_01G228700.
DR   eggNOG; ENOG502QRSY; Eukaryota.
DR   HOGENOM; CLU_034992_2_0_1; -.
DR   InParanoid; P30081; -.
DR   OMA; ANPANEM; -.
DR   OrthoDB; 950070at2759; -.
DR   BRENDA; 2.3.1.74; 2483.
DR   UniPathway; UPA00154; -.
DR   Proteomes; UP000008827; Chromosome 1.
DR   Genevisible; P30081; GM.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IBA:GO_Central.
DR   GO; GO:0102128; F:chalcone synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016210; F:naringenin-chalcone synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009813; P:flavonoid biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0030639; P:polyketide biosynthetic process; IBA:GO_Central.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR   InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR   InterPro; IPR018088; Chalcone/stilbene_synthase_AS.
DR   InterPro; IPR011141; Polyketide_synthase_type-III.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR11877; PTHR11877; 1.
DR   Pfam; PF02797; Chal_sti_synt_C; 1.
DR   Pfam; PF00195; Chal_sti_synt_N; 1.
DR   PIRSF; PIRSF000451; PKS_III; 1.
DR   SUPFAM; SSF53901; SSF53901; 2.
DR   PROSITE; PS00441; CHALCONE_SYNTH; 1.
PE   3: Inferred from homology;
KW   Acyltransferase; Flavonoid biosynthesis; Reference proteome; Transferase.
FT   CHAIN           1..389
FT                   /note="Chalcone synthase 7"
FT                   /id="PRO_0000216067"
FT   ACT_SITE        164
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10023"
SQ   SEQUENCE   389 AA;  42874 MW;  0822D18CDFFC2587 CRC64;
     MVSVAEIRQA QRAEGPATIL AIGTANPPNR VDQSTYPDYY FRITNSDHMT ELKEKFQRMC
     DKSMIKTRYM YLNEEILKEN PNMCAYMAPS LDARQDMVVV EVPKLGKEAA VKAIKEWGQP
     KSKITHLIFC TTSGVDMPGA DYQLTKQLGL RPYVKRYMMY QQGCFAGGTV LRLAKDLAEN
     NKGARVLVVC SEITAVTFRG PSDTHLDSLV GQALFGDGAA AVIVGSDPIP QVEKPLYELV
     WTAQTIAPDS EGAIDGHLRE VGLTFHLLKD VPGIVSKNID KALFEAFNPL NISDYNSIFW
     IAHPGGPAIL DQVEQKLGLK PEKMKATRDV LSEYGNMSSA CVLFILDEMR RKSAENGHKT
     TGEGLEWGVL FGFGPGLTIE TVVLHSVAI