CHVE_AGRFC
ID CHVE_AGRFC Reviewed; 354 AA.
AC P25548;
DT 01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 2.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=Multiple sugar-binding periplasmic receptor ChvE;
DE Flags: Precursor;
GN Name=chvE; OrderedLocusNames=Atu2348; ORFNames=AGR_C_4267;
OS Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens
OS (strain C58)).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium;
OC Agrobacterium tumefaciens complex.
OX NCBI_TaxID=176299;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8253785; DOI=10.1016/s0021-9258(19)74348-8;
RA Shimoda N., Toyoda-Yamamoto A., Aoki S., Machida Y.;
RT "Genetic evidence for an interaction between the VirA sensor protein and
RT the ChvE sugar-binding protein of Agrobacterium.";
RL J. Biol. Chem. 268:26552-26558(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2156804; DOI=10.1128/jb.172.4.1814-1822.1990;
RA Huang M.-L.W., Cangelosi G.A., Halperin W., Nester E.W.;
RT "A chromosomal Agrobacterium tumefaciens gene required for effective plant
RT signal transduction.";
RL J. Bacteriol. 172:1814-1822(1990).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C58 / ATCC 33970;
RX PubMed=11743193; DOI=10.1126/science.1066804;
RA Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K.,
RA Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y.,
RA Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P.,
RA Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R.,
RA Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G.,
RA Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y.,
RA Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S.,
RA Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F.,
RA Gordon M.P., Olson M.V., Nester E.W.;
RT "The genome of the natural genetic engineer Agrobacterium tumefaciens
RT C58.";
RL Science 294:2317-2323(2001).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C58 / ATCC 33970;
RX PubMed=11743194; DOI=10.1126/science.1066803;
RA Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B.,
RA Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K.,
RA Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M.,
RA Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C.,
RA Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
RT "Genome sequence of the plant pathogen and biotechnology agent
RT Agrobacterium tumefaciens C58.";
RL Science 294:2323-2328(2001).
CC -!- FUNCTION: Required for effective transcriptional induction of the vir
CC genes by monosaccharides in response to plant signals and for normal
CC growth and chemotaxis towards certain sugars. Functions as a
CC periplasmic multiple sugar-binding receptor protein. It does not
CC interact with a transport system.
CC -!- SUBCELLULAR LOCATION: Periplasm.
CC -!- INDUCTION: By L-arabinose, D-galactose, D-fucose in the presence of
CC GbpR (galactose-binding protein regulator).
CC -!- SIMILARITY: Belongs to the bacterial solute-binding protein 2 family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAA22109.1; Type=Frameshift; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; D17457; BAA04267.1; -; Genomic_DNA.
DR EMBL; M30318; AAA22109.1; ALT_FRAME; Genomic_DNA.
DR EMBL; AE007869; AAK88091.1; -; Genomic_DNA.
DR PIR; A43654; A43654.
DR PIR; AC2865; AC2865.
DR PIR; B97642; B97642.
DR RefSeq; NP_355306.1; NC_003062.2.
DR RefSeq; WP_006311697.1; NC_003062.2.
DR PDB; 3URM; X-ray; 1.80 A; A/B=25-354.
DR PDB; 3UUG; X-ray; 1.75 A; A/B=25-354.
DR PDBsum; 3URM; -.
DR PDBsum; 3UUG; -.
DR AlphaFoldDB; P25548; -.
DR SMR; P25548; -.
DR STRING; 176299.Atu2348; -.
DR TCDB; 3.A.1.2.5; the atp-binding cassette (abc) superfamily.
DR EnsemblBacteria; AAK88091; AAK88091; Atu2348.
DR GeneID; 66222541; -.
DR KEGG; atu:Atu2348; -.
DR PATRIC; fig|176299.10.peg.2362; -.
DR eggNOG; COG4213; Bacteria.
DR HOGENOM; CLU_037628_13_1_5; -.
DR OMA; SARWIDD; -.
DR PhylomeDB; P25548; -.
DR BioCyc; AGRO:ATU2348-MON; -.
DR Proteomes; UP000000813; Chromosome circular.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR025997; SBP_2_dom.
DR Pfam; PF13407; Peripla_BP_4; 1.
DR SUPFAM; SSF53822; SSF53822; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Chemotaxis; Crown gall tumor; Periplasm; Reference proteome;
KW Signal.
FT SIGNAL 1..25
FT /evidence="ECO:0000255"
FT CHAIN 26..354
FT /note="Multiple sugar-binding periplasmic receptor ChvE"
FT /id="PRO_0000031740"
FT STRAND 29..34
FT /evidence="ECO:0007829|PDB:3UUG"
FT STRAND 37..39
FT /evidence="ECO:0007829|PDB:3UUG"
FT HELIX 41..55
FT /evidence="ECO:0007829|PDB:3UUG"
FT STRAND 59..64
FT /evidence="ECO:0007829|PDB:3UUG"
FT HELIX 69..82
FT /evidence="ECO:0007829|PDB:3UUG"
FT STRAND 85..89
FT /evidence="ECO:0007829|PDB:3UUG"
FT HELIX 94..97
FT /evidence="ECO:0007829|PDB:3UUG"
FT HELIX 98..106
FT /evidence="ECO:0007829|PDB:3UUG"
FT STRAND 110..116
FT /evidence="ECO:0007829|PDB:3UUG"
FT STRAND 126..130
FT /evidence="ECO:0007829|PDB:3UUG"
FT HELIX 132..147
FT /evidence="ECO:0007829|PDB:3UUG"
FT HELIX 149..151
FT /evidence="ECO:0007829|PDB:3UUG"
FT STRAND 156..160
FT /evidence="ECO:0007829|PDB:3UUG"
FT HELIX 168..186
FT /evidence="ECO:0007829|PDB:3UUG"
FT STRAND 189..191
FT /evidence="ECO:0007829|PDB:3UUG"
FT HELIX 199..202
FT /evidence="ECO:0007829|PDB:3UUG"
FT HELIX 205..207
FT /evidence="ECO:0007829|PDB:3UUG"
FT HELIX 209..223
FT /evidence="ECO:0007829|PDB:3UUG"
FT STRAND 225..227
FT /evidence="ECO:0007829|PDB:3UUG"
FT STRAND 231..233
FT /evidence="ECO:0007829|PDB:3UUG"
FT HELIX 237..249
FT /evidence="ECO:0007829|PDB:3UUG"
FT STRAND 253..257
FT /evidence="ECO:0007829|PDB:3UUG"
FT HELIX 269..276
FT /evidence="ECO:0007829|PDB:3UUG"
FT STRAND 283..285
FT /evidence="ECO:0007829|PDB:3UUG"
FT HELIX 288..303
FT /evidence="ECO:0007829|PDB:3UUG"
FT STRAND 311..315
FT /evidence="ECO:0007829|PDB:3UUG"
FT STRAND 325..328
FT /evidence="ECO:0007829|PDB:3UUG"
FT STRAND 331..333
FT /evidence="ECO:0007829|PDB:3UUG"
FT TURN 335..337
FT /evidence="ECO:0007829|PDB:3UUG"
FT HELIX 338..342
FT /evidence="ECO:0007829|PDB:3UUG"
FT TURN 343..345
FT /evidence="ECO:0007829|PDB:3UUG"
FT STRAND 346..348
FT /evidence="ECO:0007829|PDB:3UUG"
FT HELIX 350..353
FT /evidence="ECO:0007829|PDB:3UUG"
SQ SEQUENCE 354 AA; 38129 MW; 7EEBBE5B03530EEF CRC64;
MKSIISLMAA CAIGAASFAA PAFAQDKGSV GIAMPTKSSA RWIDDGNNIV KQLQEAGYKT
DLQYADDDIP NQLSQIENMV TKGVKVLVIA SIDGTTLSDV LKQAGEQGIK VIAYDRLIRN
SGDVSYYATF DNFQVGVLQA TSITDKLGLK DGKGPFNIEL FGGSPDDNNA FFFYDGAMSV
LKPYIDSGKL VVKSGQMGMD KVGTLRWDPA TAQARMDNLL SAYYTDAKVD AVLSPYDGLS
IGIISSLKGV GYGTKDQPLP VVSGQDAEVP SVKSIIAGEQ YSTIFKDTRE LAKVTVNMVN
AVMEGKEPEV NDTKTYENGV KVVPSYLLKP VAVTKENYKQ VLVDGGYYKE DQLK
