CHX7_ARATH
ID CHX7_ARATH Reviewed; 801 AA.
AC Q9ZUV9;
DT 15-JUN-2010, integrated into UniProtKB/Swiss-Prot.
DT 15-JUN-2010, sequence version 2.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Cation/H(+) antiporter 7;
DE AltName: Full=Protein CATION/H+ EXCHANGER 7;
DE Short=AtCHX7;
GN Name=CHX7; Synonyms=CHX07; OrderedLocusNames=At2g28170; ORFNames=F24D13.4;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11500563; DOI=10.1104/pp.126.4.1646;
RA Maeser P., Thomine S., Schroeder J.I., Ward J.M., Hirschi K., Sze H.,
RA Talke I.N., Amtmann A., Maathuis F.J.M., Sanders D., Harper J.F.,
RA Tchieu J., Gribskov M., Persans M.W., Salt D.E., Kim S.A., Guerinot M.L.;
RT "Phylogenetic relationships within cation transporter families of
RT Arabidopsis.";
RL Plant Physiol. 126:1646-1667(2001).
RN [4]
RP TISSUE SPECIFICITY, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=15347787; DOI=10.1104/pp.104.046003;
RA Sze H., Padmanaban S., Cellier F., Honys D., Cheng N.-H., Bock K.W.,
RA Conejero G., Li X., Twell D., Ward J.M., Hirschi K.D.;
RT "Expression patterns of a novel AtCHX gene family highlight potential roles
RT in osmotic adjustment and K+ homeostasis in pollen development.";
RL Plant Physiol. 136:2532-2547(2004).
CC -!- FUNCTION: May operate as a cation/H(+) antiporter. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed in pollen. {ECO:0000269|PubMed:15347787}.
CC -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 2 (CPA2)
CC transporter (TC 2.A.37) family. CHX (TC 2.A.37.4) subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC98449.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC005851; AAC98449.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002685; AEC08087.1; -; Genomic_DNA.
DR PIR; F84681; F84681.
DR RefSeq; NP_180384.2; NM_128377.2.
DR AlphaFoldDB; Q9ZUV9; -.
DR PaxDb; Q9ZUV9; -.
DR PRIDE; Q9ZUV9; -.
DR EnsemblPlants; AT2G28170.1; AT2G28170.1; AT2G28170.
DR GeneID; 817363; -.
DR Gramene; AT2G28170.1; AT2G28170.1; AT2G28170.
DR KEGG; ath:AT2G28170; -.
DR Araport; AT2G28170; -.
DR TAIR; locus:2046188; AT2G28170.
DR eggNOG; KOG1650; Eukaryota.
DR HOGENOM; CLU_005126_6_1_1; -.
DR InParanoid; Q9ZUV9; -.
DR OMA; DGFICEV; -.
DR OrthoDB; 336706at2759; -.
DR PhylomeDB; Q9ZUV9; -.
DR PRO; PR:Q9ZUV9; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9ZUV9; differential.
DR Genevisible; Q9ZUV9; AT.
DR GO; GO:0012505; C:endomembrane system; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015299; F:solute:proton antiporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.
DR GO; GO:0006885; P:regulation of pH; IBA:GO_Central.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR Pfam; PF00999; Na_H_Exchanger; 1.
PE 2: Evidence at transcript level;
KW Antiport; Ion transport; Membrane; Potassium; Potassium transport;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..801
FT /note="Cation/H(+) antiporter 7"
FT /id="PRO_0000394978"
FT TRANSMEM 58..78
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 83..103
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 128..148
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 154..174
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 192..212
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 223..243
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 254..274
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 287..307
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 312..332
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 340..360
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 377..397
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 407..427
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 438..458
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 801 AA; 90990 MW; D264503CA5D17796 CRC64;
MDPFNASWWT NMAWHGYSLS EDGTKFCEML PTKINSFGLS EKILHKSVGL YFWEYPLPNL
ELIILSVFFF WQFFEILFKM SNIPIPKMPS MMLGCVVINL FSYTRPGSLL HRMFFPDDGR
PKVAETGGAF GFVMYWFLKG VSIDVGMLRK TEPRAALIGF NTLVIPYISG YILMRTRKHF
GKLAMTELQY QEIILLQSLS SFAGVNGLLT DLKINHSEFG RMVQSCAAVT DLVIFIMVSG
TVLLKGQKGL PHGIVIVLVI GFLVYIVWPV MLWIIKQTPE GRLVKDVYIY LVMATAYFVY
MFWLNFFQFS TYGWFIIGLA TPAGPPLGSA LIQRFECFNV GVLLPLFGSL SMEQLDISWL
MREILNLKHM EGFAYEAISV ILIVTVVKFV VTAITAFAVR IPYRDSIVLA MVLSNRSIFE
LGYLGYIVEL KMFDNKSFTI AALSVLVSSL LTPIAIEFMY EPQHIFSSYR DRNMLTLKHD
SKLKTLVCIH KPDHITSMVN FVELFNPTQE SKLECNVLHL VELIGQAIPT FISHKMQKPK
VGTRSCSRNV ITAFLSLRRH LTKEAISIDI FTSASLVEHM HEDLCWLALD KNVALVVLPF
HRSWSVDRST IVSDDKAMQN LNHKVLKRAS CSVGIFVYRK PLWESQMHGS CYKVCAIVVG
GKDDKEALAF TNRMRRNKQT SVTILHLIPQ LTTEESEDSV QKLDYDDIKE IMKTEDSNEN
DSWICIEKSV KEGAETSVIL RSIAYDYDLF IVGRSSGMNS AVTKGLNEWT EFEELGALGD
VIASKEFPSR ASVLVLQQQQ Y
