CI040_MOUSE
ID CI040_MOUSE Reviewed; 163 AA.
AC Q8VCE4; Q8BJJ5;
DT 16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Uncharacterized protein C9orf40 homolog;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=FVB/N; TISSUE=Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-102, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
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DR EMBL; AK083631; BAC38973.1; -; mRNA.
DR EMBL; BC020125; AAH20125.1; -; mRNA.
DR RefSeq; NP_808308.1; NM_177640.4.
DR AlphaFoldDB; Q8VCE4; -.
DR IntAct; Q8VCE4; 1.
DR STRING; 10090.ENSMUSP00000108465; -.
DR iPTMnet; Q8VCE4; -.
DR PhosphoSitePlus; Q8VCE4; -.
DR EPD; Q8VCE4; -.
DR MaxQB; Q8VCE4; -.
DR PaxDb; Q8VCE4; -.
DR PRIDE; Q8VCE4; -.
DR Antibodypedia; 43431; 61 antibodies from 14 providers.
DR Ensembl; ENSMUST00000062753; ENSMUSP00000108465; ENSMUSG00000047044.
DR GeneID; 225995; -.
DR KEGG; mmu:225995; -.
DR UCSC; uc008gxz.1; mouse.
DR MGI; MGI:3583960; D030056L22Rik.
DR VEuPathDB; HostDB:ENSMUSG00000047044; -.
DR eggNOG; ENOG502SEFF; Eukaryota.
DR GeneTree; ENSGT00390000001325; -.
DR HOGENOM; CLU_117698_1_0_1; -.
DR InParanoid; Q8VCE4; -.
DR OMA; RQHNEEF; -.
DR OrthoDB; 1435359at2759; -.
DR PhylomeDB; Q8VCE4; -.
DR TreeFam; TF338442; -.
DR BioGRID-ORCS; 225995; 2 hits in 71 CRISPR screens.
DR PRO; PR:Q8VCE4; -.
DR Proteomes; UP000000589; Chromosome 19.
DR RNAct; Q8VCE4; protein.
DR Bgee; ENSMUSG00000047044; Expressed in rostral migratory stream and 252 other tissues.
DR ExpressionAtlas; Q8VCE4; baseline and differential.
DR Genevisible; Q8VCE4; MM.
DR InterPro; IPR042349; C9orf40-like.
DR InterPro; IPR033461; WRNPLPNID.
DR PANTHER; PTHR16003; PTHR16003; 1.
DR Pfam; PF15017; WRNPLPNID; 1.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..163
FT /note="Uncharacterized protein C9orf40 homolog"
FT /id="PRO_0000089683"
FT REGION 23..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 58..73
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 102
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:21183079"
FT CONFLICT 112
FT /note="Missing (in Ref. 1; BAC38973)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 163 AA; 17985 MW; 30D15A98276DF9DF CRC64;
MAKRRAAEPL TFRVPWKRLL LSDFPEEPPL WVPPSGTARP LKRQGDAGIM AEPASAPRKR
RGGGDDRQEL QGCSREPGEP PPGEQEEPRA AGGGDRVESA GSPQVADGVH SQQPEEFWQY
NTFQYWRNPL PPLDLAALED VSANSLTETL EDKNEGVEID MES