ID   CI092_HUMAN             Reviewed;          77 AA.
AC   A6NGG3; A6NMF8;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2007, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Putative uncharacterized protein C9orf92;
GN   Name=C9orf92;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RX   PubMed=11329013; DOI=10.1038/88107;
RA   Harrington J.J., Sherf B., Rundlett S., Jackson P.D., Perry R., Cain S.,
RA   Leventhal C., Thornton M., Ramachandran R., Whittington J., Lerner L.,
RA   Costanzo D., McElligott K., Boozer S., Mays R., Smith E., Veloso N.,
RA   Klika A., Hess J., Cothren K., Lo K., Offenbacher J., Danzig J., Ducar M.;
RT   "Creation of genome-wide protein expression libraries using random
RT   activation of gene expression.";
RL   Nat. Biotechnol. 19:440-445(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15164053; DOI=10.1038/nature02465;
RA   Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L.,
RA   Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R.,
RA   Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S.,
RA   Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K.,
RA   Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y.,
RA   Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C.,
RA   Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E.,
RA   Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M.,
RA   Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J.,
RA   Frankish A., Frankland J.A., French L., Fricker D.G., Garner P.,
RA   Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S.,
RA   Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E.,
RA   Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D.,
RA   Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E.,
RA   Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K.,
RA   Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S.,
RA   Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J.,
RA   Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E.,
RA   McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V.,
RA   Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S.,
RA   Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K.,
RA   Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J.,
RA   Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M.,
RA   West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L.,
RA   Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M.,
RA   Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J.,
RA   Dunham I.;
RT   "DNA sequence and analysis of human chromosome 9.";
RL   Nature 429:369-374(2004).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=A6NGG3-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=A6NGG3-2; Sequence=VSP_030775;
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DR   EMBL; BG220529; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; AL513424; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001258758.1; NM_001271829.1.
DR   AlphaFoldDB; A6NGG3; -.
DR   STRING; 9606.ENSP00000370058; -.
DR   BioMuta; C9orf92; -.
DR   PaxDb; A6NGG3; -.
DR   PRIDE; A6NGG3; -.
DR   ProteomicsDB; 1123; -. [A6NGG3-1]
DR   ProteomicsDB; 1124; -. [A6NGG3-2]
DR   DNASU; 100129385; -.
DR   GeneID; 100129385; -.
DR   UCSC; uc031tcu.2; human. [A6NGG3-1]
DR   CTD; 100129385; -.
DR   DisGeNET; 100129385; -.
DR   GeneCards; C9orf92; -.
DR   HGNC; HGNC:19054; C9orf92.
DR   neXtProt; NX_A6NGG3; -.
DR   eggNOG; ENOG502TJYE; Eukaryota.
DR   HOGENOM; CLU_176670_0_0_1; -.
DR   InParanoid; A6NGG3; -.
DR   OrthoDB; 1466228at2759; -.
DR   TreeFam; TF354093; -.
DR   PathwayCommons; A6NGG3; -.
DR   BioGRID-ORCS; 100129385; 7 hits in 1010 CRISPR screens.
DR   ChiTaRS; C9orf92; human.
DR   Pharos; A6NGG3; Tdark.
DR   PRO; PR:A6NGG3; -.
DR   Proteomes; UP000005640; Chromosome 9.
DR   RNAct; A6NGG3; protein.
DR   InterPro; IPR040507; DUF5540.
DR   Pfam; PF17694; DUF5540; 1.
PE   4: Predicted;
KW   Alternative splicing; Reference proteome.
FT   CHAIN           1..77
FT                   /note="Putative uncharacterized protein C9orf92"
FT                   /id="PRO_0000316783"
FT   VAR_SEQ         1
FT                   /note="M -> MELNTNIKSKKGLGRRNLKPMNGAWPPARREM (in isoform
FT                   2)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_030775"
FT   CONFLICT        27
FT                   /note="Q -> R (in Ref. 1; BG220529)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        72
FT                   /note="S -> P (in Ref. 1; BG220529)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   77 AA;  8520 MW;  215CD74E88B64771 CRC64;
     MARFQRTKER EEDRCSLNIY YVRNTTQGTA PACVGKRMQP SPTGKGGKCC TVHGLTRKIH
     NVQPNLQSPI LSAACVD