CI131_MOUSE
ID CI131_MOUSE Reviewed; 1183 AA.
AC Q3V0E1; A2AG32; Q9CVP8; Q9CVW7;
DT 10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2005, sequence version 1.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=Uncharacterized protein C9orf131 homolog;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
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DR EMBL; AK006242; BAB24476.1; -; mRNA.
DR EMBL; AK007056; BAB24843.3; -; mRNA.
DR EMBL; AK133216; BAE21563.1; -; mRNA.
DR EMBL; AL672276; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS51160.1; -.
DR RefSeq; NP_080364.1; NM_026088.3.
DR AlphaFoldDB; Q3V0E1; -.
DR STRING; 10090.ENSMUSP00000030163; -.
DR iPTMnet; Q3V0E1; -.
DR PhosphoSitePlus; Q3V0E1; -.
DR PaxDb; Q3V0E1; -.
DR PRIDE; Q3V0E1; -.
DR Antibodypedia; 50361; 63 antibodies from 4 providers.
DR Ensembl; ENSMUST00000030163; ENSMUSP00000030163; ENSMUSG00000028451.
DR GeneID; 67317; -.
DR KEGG; mmu:67317; -.
DR UCSC; uc008soq.2; mouse.
DR MGI; MGI:1914567; 1700022I11Rik.
DR VEuPathDB; HostDB:ENSMUSG00000028451; -.
DR eggNOG; ENOG502RJ23; Eukaryota.
DR GeneTree; ENSGT00390000000748; -.
DR HOGENOM; CLU_010861_0_0_1; -.
DR InParanoid; Q3V0E1; -.
DR OMA; WHWSREL; -.
DR OrthoDB; 200462at2759; -.
DR PhylomeDB; Q3V0E1; -.
DR TreeFam; TF337467; -.
DR BioGRID-ORCS; 67317; 2 hits in 71 CRISPR screens.
DR PRO; PR:Q3V0E1; -.
DR Proteomes; UP000000589; Chromosome 4.
DR RNAct; Q3V0E1; protein.
DR Bgee; ENSMUSG00000028451; Expressed in spermatid and 36 other tissues.
DR ExpressionAtlas; Q3V0E1; baseline and differential.
DR InterPro; IPR026677; UPF_C9orf131.
DR PANTHER; PTHR21777; PTHR21777; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..1183
FT /note="Uncharacterized protein C9orf131 homolog"
FT /id="PRO_0000294444"
FT REGION 109..153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 469..555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 661..686
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 843..884
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 973..1032
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1048..1087
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 133..153
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 489..507
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 973..989
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 126
FT /note="S -> F (in Ref. 1; BAB24476)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 1183 AA; 130387 MW; 8F44D04C5CF31052 CRC64;
MGLLQGQLTH ALACRHCSSI TCLHSPGNLA ILVLFMVWQI RRWWQLRGWQ QLQPWCSGDK
MTQGKGLQLL YHLAFFDCLW KQKSEEEEKE EKECLSLNPL KPYHLSKDTP IGNGFSTAPP
HPSCRSEGRP RATETQEQVL IQSPSPSRSF PTFQTLTNLP VRSKRASGSS PQQTKLQLFS
GLPSLYNESL KTIFLSSDGP SPLKLSICPS VFLNKVPFPP AYNLLLPCYH SSTYYPTPEA
HILEDLEEIA PGSQLVQSPP SPPIPLVSSN LKPLLKGYKR IIPDTEVHTQ WFTQNKEVPS
VSENQGLYPQ PELQKFRSST FLYSSEVWRK RPGDLRLHQH NPELPFAFLL YPFNPQEVLD
RFEMPWRNMK QNEHPKASET AMPTASPLPI SLTECQRVNP TGDLSQVKTL CQTTVQKENL
QIYELPISAP CQLTVPVTEG TGPPGTPPGY EAQWGILAYK GIPQASDPLM PASCHPSGSL
SKVKNVNPKE RLSAPKDVRE NLGYREHPHV SKSPVSAPSP PLDTLSDYQR ENPPEDGSGF
KPQWECKETS GSPWASETPT LDFHVGFYEA TPMCVPLGSE AQLKGTPSTE NLCVYADIVS
SPSLPSVSLP DFAIMGPQRI LLESKALWET KEQKKHLWTS DSSCPHKTPL APFIGPKRIN
TVDDVPRSEA TGKNTDNTKK CSSSEPPFLN LNPSPALVQQ PLRVSPIENP LKSKAWCGHI
QRKNNFLASE LPAQSLSQHL LEPSPEGVLS DVEPAGGFMK NKNHCVSASP VWECSPSPNS
VLKFHISEPS GDQCNCTPKE SVAEWTKDSW ANELPGSSFF SALSQEPHSE TELVCRNVLE
REASQGPNPP AVNPPQPTAW PIQPGLSEAK AEAPSSQGEA VSEVSDHPVI HAWQWSRQLK
LRLNKLQQSP TFKSPGSHHS FSSSPVLNLT LESWGPSSCS QQMHPLSLHP CSSSSHPPKV
QRAEALPVQA PHCLHSSSQP QAQASGRAEQ RSQKSKRLKR KAMVQIPSPG LGHVKADENC
SGMGEPSDTG LLVSGKRQDK TLVLLSTQKR GSSRKSKAEK CGRTARLGSP TNTRENNPAQ
ACRPAEASMP RFSRKFEHKA QSSPHSALAQ QLLPNAAGPQ DRPRTGLVAG ETQNPCPFKC
CPWIPTKQQL SSLSQEAPPT RGFQKLIDKF LGVHRPLPTK SSP