CI152_HUMAN
ID CI152_HUMAN Reviewed; 239 AA.
AC Q5JTZ5; A8MWT6;
DT 04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT 02-SEP-2008, sequence version 2.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Uncharacterized protein C9orf152;
GN Name=C9orf152;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15164053; DOI=10.1038/nature02465;
RA Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L.,
RA Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R.,
RA Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S.,
RA Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K.,
RA Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y.,
RA Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C.,
RA Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E.,
RA Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M.,
RA Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J.,
RA Frankish A., Frankland J.A., French L., Fricker D.G., Garner P.,
RA Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S.,
RA Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E.,
RA Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D.,
RA Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E.,
RA Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K.,
RA Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S.,
RA Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J.,
RA Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E.,
RA McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V.,
RA Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S.,
RA Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K.,
RA Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J.,
RA Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M.,
RA West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L.,
RA Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M.,
RA Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J.,
RA Dunham I.;
RT "DNA sequence and analysis of human chromosome 9.";
RL Nature 429:369-374(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 19-239.
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- INTERACTION:
CC Q5JTZ5; Q49AR9: ANKS1A; NbExp=3; IntAct=EBI-18560658, EBI-11954519;
CC Q5JTZ5; P40692: MLH1; NbExp=3; IntAct=EBI-18560658, EBI-744248;
CC -!- SEQUENCE CAUTION:
CC Sequence=AAI10808.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AL353598; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC110807; AAI10808.1; ALT_INIT; mRNA.
DR CCDS; CCDS35102.2; -.
DR RefSeq; NP_001013011.2; NM_001012993.2.
DR AlphaFoldDB; Q5JTZ5; -.
DR BioGRID; 135141; 8.
DR IntAct; Q5JTZ5; 2.
DR STRING; 9606.ENSP00000383456; -.
DR iPTMnet; Q5JTZ5; -.
DR PhosphoSitePlus; Q5JTZ5; -.
DR BioMuta; C9orf152; -.
DR DMDM; 205371744; -.
DR jPOST; Q5JTZ5; -.
DR MassIVE; Q5JTZ5; -.
DR PaxDb; Q5JTZ5; -.
DR PeptideAtlas; Q5JTZ5; -.
DR PRIDE; Q5JTZ5; -.
DR ProteomicsDB; 63244; -.
DR Antibodypedia; 29459; 61 antibodies from 11 providers.
DR DNASU; 401546; -.
DR Ensembl; ENST00000400613.5; ENSP00000383456.4; ENSG00000188959.10.
DR GeneID; 401546; -.
DR KEGG; hsa:401546; -.
DR MANE-Select; ENST00000400613.5; ENSP00000383456.4; NM_001012993.3; NP_001013011.2.
DR UCSC; uc011lwk.3; human.
DR CTD; 401546; -.
DR GeneCards; C9orf152; -.
DR HGNC; HGNC:31455; C9orf152.
DR HPA; ENSG00000188959; Tissue enhanced (intestine, salivary gland, stomach).
DR neXtProt; NX_Q5JTZ5; -.
DR OpenTargets; ENSG00000188959; -.
DR PharmGKB; PA134988229; -.
DR VEuPathDB; HostDB:ENSG00000188959; -.
DR eggNOG; ENOG502SBBU; Eukaryota.
DR GeneTree; ENSGT00390000005322; -.
DR HOGENOM; CLU_111626_0_0_1; -.
DR InParanoid; Q5JTZ5; -.
DR OMA; VGNTQTK; -.
DR OrthoDB; 1528623at2759; -.
DR PhylomeDB; Q5JTZ5; -.
DR TreeFam; TF337454; -.
DR PathwayCommons; Q5JTZ5; -.
DR SignaLink; Q5JTZ5; -.
DR BioGRID-ORCS; 401546; 11 hits in 1049 CRISPR screens.
DR ChiTaRS; C9orf152; human.
DR GenomeRNAi; 401546; -.
DR Pharos; Q5JTZ5; Tdark.
DR PRO; PR:Q5JTZ5; -.
DR Proteomes; UP000005640; Chromosome 9.
DR RNAct; Q5JTZ5; protein.
DR Bgee; ENSG00000188959; Expressed in ileal mucosa and 115 other tissues.
DR Genevisible; Q5JTZ5; HS.
DR InterPro; IPR032738; Tbc1d30_C.
DR Pfam; PF15733; DUF4682; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..239
FT /note="Uncharacterized protein C9orf152"
FT /id="PRO_0000229729"
SQ SEQUENCE 239 AA; 26314 MW; 0115E974BE590A1D CRC64;
MEGLPCPCPA LPHFWQLRSH LMAEGSRTQA PGKGPPLSIQ FLRAQYEGLK RQQRTQAHLL
VLPKGGNTPA PAESMVNAVW INKERRSSLS LEEADSEVEG RLEEAAQGCL QAPKSPWHTH
LEMHCLVQTS PQDTSHQVHH RGKLVGSDQR LPPEGDTHLF ETNQMTQQGT GIPEAAQLPC
QVGNTQTKAV ESGLKFSTQC PLSIKNPHRS GKPAYYPFPQ RKTPRISQAA RNLGLYGSA