CI153_HUMAN
ID CI153_HUMAN Reviewed; 101 AA.
AC Q5TBE3; Q5TBE4;
DT 04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT 21-DEC-2004, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Uncharacterized protein C9orf153;
GN Name=C9orf153;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15164053; DOI=10.1038/nature02465;
RA Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L.,
RA Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R.,
RA Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S.,
RA Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K.,
RA Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y.,
RA Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C.,
RA Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E.,
RA Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M.,
RA Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J.,
RA Frankish A., Frankland J.A., French L., Fricker D.G., Garner P.,
RA Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S.,
RA Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E.,
RA Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D.,
RA Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E.,
RA Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K.,
RA Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S.,
RA Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J.,
RA Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E.,
RA McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V.,
RA Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S.,
RA Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K.,
RA Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J.,
RA Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M.,
RA West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L.,
RA Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M.,
RA Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J.,
RA Dunham I.;
RT "DNA sequence and analysis of human chromosome 9.";
RL Nature 429:369-374(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- INTERACTION:
CC Q5TBE3-2; Q8IYR0: CFAP206; NbExp=3; IntAct=EBI-12159293, EBI-749051;
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q5TBE3-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q5TBE3-2; Sequence=VSP_017734;
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DR EMBL; AL137849; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC108665; AAI08666.1; -; mRNA.
DR CCDS; CCDS35055.2; -. [Q5TBE3-2]
DR RefSeq; NP_001263295.1; NM_001276366.1. [Q5TBE3-2]
DR RefSeq; NP_001263296.1; NM_001276367.1. [Q5TBE3-2]
DR RefSeq; NP_001263297.1; NM_001276368.1. [Q5TBE3-2]
DR AlphaFoldDB; Q5TBE3; -.
DR SMR; Q5TBE3; -.
DR BioGRID; 133263; 2.
DR IntAct; Q5TBE3; 1.
DR STRING; 9606.ENSP00000344865; -.
DR iPTMnet; Q5TBE3; -.
DR PhosphoSitePlus; Q5TBE3; -.
DR BioMuta; C9orf153; -.
DR DMDM; 74745945; -.
DR MassIVE; Q5TBE3; -.
DR PaxDb; Q5TBE3; -.
DR PeptideAtlas; Q5TBE3; -.
DR PRIDE; Q5TBE3; -.
DR ProteomicsDB; 64900; -. [Q5TBE3-2]
DR Antibodypedia; 27804; 61 antibodies from 16 providers.
DR DNASU; 389766; -.
DR Ensembl; ENST00000339137.7; ENSP00000344865.2; ENSG00000187753.13. [Q5TBE3-2]
DR Ensembl; ENST00000376001.7; ENSP00000365169.3; ENSG00000187753.13. [Q5TBE3-1]
DR Ensembl; ENST00000613665.4; ENSP00000484453.1; ENSG00000187753.13. [Q5TBE3-2]
DR Ensembl; ENST00000617985.1; ENSP00000484765.1; ENSG00000187753.13. [Q5TBE3-1]
DR GeneID; 389766; -.
DR KEGG; hsa:389766; -.
DR MANE-Select; ENST00000339137.7; ENSP00000344865.2; NM_001276366.4; NP_001263295.1. [Q5TBE3-2]
DR UCSC; uc031teh.1; human. [Q5TBE3-1]
DR CTD; 389766; -.
DR DisGeNET; 389766; -.
DR GeneCards; C9orf153; -.
DR HGNC; HGNC:31456; C9orf153.
DR HPA; ENSG00000187753; Tissue enriched (testis).
DR neXtProt; NX_Q5TBE3; -.
DR OpenTargets; ENSG00000187753; -.
DR PharmGKB; PA134962664; -.
DR VEuPathDB; HostDB:ENSG00000187753; -.
DR eggNOG; ENOG502TJJH; Eukaryota.
DR GeneTree; ENSGT00940000164155; -.
DR HOGENOM; CLU_180164_0_0_1; -.
DR InParanoid; Q5TBE3; -.
DR OMA; FRKTIHG; -.
DR OrthoDB; 1533514at2759; -.
DR PhylomeDB; Q5TBE3; -.
DR PathwayCommons; Q5TBE3; -.
DR SignaLink; Q5TBE3; -.
DR BioGRID-ORCS; 389766; 16 hits in 1054 CRISPR screens.
DR GenomeRNAi; 389766; -.
DR Pharos; Q5TBE3; Tdark.
DR PRO; PR:Q5TBE3; -.
DR Proteomes; UP000005640; Chromosome 9.
DR RNAct; Q5TBE3; protein.
DR Bgee; ENSG00000187753; Expressed in left testis and 83 other tissues.
DR ExpressionAtlas; Q5TBE3; baseline and differential.
DR InterPro; IPR040022; C9orf153-like.
DR PANTHER; PTHR37353; PTHR37353; 1.
DR Pfam; PF17673; DUF5532; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..101
FT /note="Uncharacterized protein C9orf153"
FT /id="PRO_0000229730"
FT VAR_SEQ 81..101
FT /note="SVNKMNKPGKHRKTPSPKINK -> RKTIHESKGSGMEIF (in isoform
FT 2)"
FT /evidence="ECO:0000303|PubMed:15489334"
FT /id="VSP_017734"
SQ SEQUENCE 101 AA; 11254 MW; 385A75FF4DB0AEE6 CRC64;
MFLTGDTSPA EDNREATLPQ CSLPELYACI ENFNKESKKS NLLKMHGISL NEAQEVLARN
LNVMSFTRGA DVRGDLQPVI SVNKMNKPGK HRKTPSPKIN K
