ID   CIA2B_DICDI             Reviewed;         163 AA.
AC   Q54QK1;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   19-JAN-2010, sequence version 2.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Cytosolic iron-sulfur assembly component 2B {ECO:0000305};
GN   Name=ciao2B {ECO:0000250|UniProtKB:Q9Y3D0}; Synonyms=fam96B;
GN   ORFNames=DDB_G0283801;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Component of the cytosolic iron-sulfur (Fe/S) protein
CC       assembly machinery. Required for the maturation of extramitochondrial
CC       Fe/S proteins. May play a role in chromosome segregation through
CC       establishment of sister chromatid cohesion.
CC       {ECO:0000250|UniProtKB:Q9Y3D0}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9Y3D0}.
CC       Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q9Y3D0}.
CC   -!- SIMILARITY: Belongs to the MIP18 family. {ECO:0000305}.
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DR   EMBL; AAFI02000057; EAL65515.2; -; Genomic_DNA.
DR   RefSeq; XP_638870.2; XM_633778.2.
DR   AlphaFoldDB; Q54QK1; -.
DR   SMR; Q54QK1; -.
DR   STRING; 44689.DDB0267133; -.
DR   PaxDb; Q54QK1; -.
DR   EnsemblProtists; EAL65515; EAL65515; DDB_G0283801.
DR   GeneID; 8624268; -.
DR   KEGG; ddi:DDB_G0283801; -.
DR   dictyBase; DDB_G0283801; fam96B.
DR   eggNOG; KOG3381; Eukaryota.
DR   HOGENOM; CLU_075876_3_1_1; -.
DR   InParanoid; Q54QK1; -.
DR   OMA; LNICSAH; -.
DR   PhylomeDB; Q54QK1; -.
DR   PRO; PR:Q54QK1; -.
DR   Proteomes; UP000002195; Chromosome 4.
DR   GO; GO:0097361; C:CIA complex; ISS:UniProtKB.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
DR   GO; GO:0106035; P:protein maturation by [4Fe-4S] cluster transfer; IEA:InterPro.
DR   GO; GO:0097428; P:protein maturation by iron-sulfur cluster transfer; ISS:UniProtKB.
DR   Gene3D; 3.30.300.130; -; 1.
DR   InterPro; IPR034904; FSCA_dom_sf.
DR   InterPro; IPR039796; MIP18.
DR   InterPro; IPR002744; MIP18-like.
DR   PANTHER; PTHR12377; PTHR12377; 1.
DR   Pfam; PF01883; FeS_assembly_P; 1.
DR   SUPFAM; SSF117916; SSF117916; 1.
PE   3: Inferred from homology;
KW   Chromosome partition; Cytoplasm; Cytoskeleton; Nucleus; Reference proteome.
FT   CHAIN           1..163
FT                   /note="Cytosolic iron-sulfur assembly component 2B"
FT                   /id="PRO_0000371407"
SQ   SEQUENCE   163 AA;  18494 MW;  CBEDFFE27B426D13 CRC64;
     MSDNPNPVIY VDNENCKSFE DNENSFNSSR YSIEEDQIDE FDEQEIFDLV RSITDPEHPL
     TLEQLNVVRI ENVNINLENS YILLYFTPTV PHCSMANLIG LSIKEKLARS LPKRFKVDVI
     VTPGSHSSES SVNKQLNDKE RVSAALDTSS SILTIVNECI KQN