位置:首页 > 蛋白库 > CIA30_CAEBR
CIA30_CAEBR
ID   CIA30_CAEBR             Reviewed;         340 AA.
AC   Q61FQ3; A8XCR5;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Probable complex I intermediate-associated protein 30, mitochondrial;
DE   AltName: Full=NADH ubiquinone oxidoreductase assembly factor 1;
DE   Flags: Precursor;
GN   Name=nuaf-1; ORFNames=CBG11538;
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16;
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- FUNCTION: Chaperone protein involved in the assembly of the
CC       mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
CC       Required for normal growth and reproduction (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CIA30 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; HE600908; CAP30433.1; -; Genomic_DNA.
DR   RefSeq; XP_002635291.1; XM_002635245.1.
DR   AlphaFoldDB; Q61FQ3; -.
DR   SMR; Q61FQ3; -.
DR   STRING; 6238.CBG11538; -.
DR   PRIDE; Q61FQ3; -.
DR   EnsemblMetazoa; CBG11538.1; CBG11538.1; WBGene00032645.
DR   GeneID; 8577287; -.
DR   KEGG; cbr:CBG_11538; -.
DR   CTD; 8577287; -.
DR   WormBase; CBG11538; CBP02779; WBGene00032645; Cbr-nuaf-1.
DR   eggNOG; KOG2435; Eukaryota.
DR   HOGENOM; CLU_059028_2_2_1; -.
DR   InParanoid; Q61FQ3; -.
DR   OMA; SMKLEDR; -.
DR   OrthoDB; 1563319at2759; -.
DR   Proteomes; UP000008549; Chromosome V.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; IBA:GO_Central.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IBA:GO_Central.
DR   GO; GO:0010257; P:NADH dehydrogenase complex assembly; IBA:GO_Central.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR013857; NADH-UbQ_OxRdtase-assoc_prot30.
DR   InterPro; IPR039131; NDUFAF1.
DR   PANTHER; PTHR13194; PTHR13194; 1.
DR   Pfam; PF08547; CIA30; 1.
DR   SUPFAM; SSF49785; SSF49785; 1.
PE   3: Inferred from homology;
KW   Chaperone; Mitochondrion; Reference proteome; Transit peptide.
FT   TRANSIT         1..?
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..340
FT                   /note="Probable complex I intermediate-associated protein
FT                   30, mitochondrial"
FT                   /id="PRO_0000251471"
SQ   SEQUENCE   340 AA;  38816 MW;  FCE1CC63F9194013 CRC64;
     MISNFTGRLL LPKFRNKLCA FFSKESTSSN SLAKSKTNSE LEGYTGKSNL LEKKKVGVFG
     TSTVPINTNF PNPKGVIGYD PDFSVKELVA ELPNTRKTQG AKLAEEIKDA FSNISIEKPE
     LLEDIGFVRH NEARVEYKFD TSEKLDLWKI GCDSDWKEGF STCSLVNSDR GTAVFSGNIS
     TRVLKDGRVE RAGWASMKLE DRKTFNRKKF LSKWRNFSHL LLKVRGDGRS YKIMLHSPLS
     MDFTWGDSFS HPLHTHGGPY WQYEKIPFSK FFHTVAGRIQ DRQYRVNLED TSSIGIVLMD
     RIDGDFKLEI DYIGVYNDTT HVEDFAYETY TLPVFNTHGF
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024