ID   CIAO1_ASPFC             Reviewed;         460 AA.
AC   B0XQ15;
DT   01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Probable cytosolic iron-sulfur protein assembly protein 1 {ECO:0000255|HAMAP-Rule:MF_03037};
GN   Name=cia1; ORFNames=AFUB_008350;
OS   Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus
OS   fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=451804;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CEA10 / CBS 144.89 / FGSC A1163;
RX   PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA   Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA   Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA   Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA   Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA   Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA   White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA   Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT   "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT   fumigatus.";
RL   PLoS Genet. 4:E1000046-E1000046(2008).
CC   -!- FUNCTION: Essential component of the cytosolic iron-sulfur (Fe/S)
CC       protein assembly machinery. Required for the maturation of
CC       extramitochondrial Fe/S proteins. {ECO:0000255|HAMAP-Rule:MF_03037}.
CC   -!- SIMILARITY: Belongs to the WD repeat CIA1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_03037}.
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DR   EMBL; DS499594; EDP56129.1; -; Genomic_DNA.
DR   AlphaFoldDB; B0XQ15; -.
DR   SMR; B0XQ15; -.
DR   EnsemblFungi; EDP56129; EDP56129; AFUB_008350.
DR   VEuPathDB; FungiDB:AFUB_008350; -.
DR   HOGENOM; CLU_000288_57_8_1; -.
DR   PhylomeDB; B0XQ15; -.
DR   Proteomes; UP000001699; Unassembled WGS sequence.
DR   GO; GO:0097361; C:CIA complex; IEA:InterPro.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.130.10.10; -; 1.
DR   HAMAP; MF_03037; ciao1; 1.
DR   InterPro; IPR028608; CIAO1/Cia1.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR19920; PTHR19920; 1.
DR   Pfam; PF00400; WD40; 3.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 4.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE   3: Inferred from homology;
KW   Repeat; WD repeat.
FT   CHAIN           1..460
FT                   /note="Probable cytosolic iron-sulfur protein assembly
FT                   protein 1"
FT                   /id="PRO_0000382501"
FT   REPEAT          17..59
FT                   /note="WD 1"
FT   REPEAT          63..105
FT                   /note="WD 2"
FT   REPEAT          151..190
FT                   /note="WD 3"
FT   REPEAT          198..237
FT                   /note="WD 4"
FT   REPEAT          242..308
FT                   /note="WD 5"
FT   REPEAT          342..381
FT                   /note="WD 6"
FT   REPEAT          416..457
FT                   /note="WD 7"
FT   REGION          301..325
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        307..322
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   460 AA;  50653 MW;  7DF8D36912653791 CRC64;
     MVMAAEASSQ LSLLSDLTPP SLERTWLTAP HPTLPIVATC SSDKTVRVYS LTNFRLLSTI
     SGGHKRSVRT CAWKPHVKGE SVLATGSFDA TVGIWRRWDS YGQTERGIED WRHADSHDHV
     DGMGAAGINN GGGDSADEDD EEWRFAVLLD GHDSEVKSVS WSPSGMLLAT CSRDKSIWIW
     EDLDDGDNNF ETVAVMQEHQ GDVKCVAWHP VEECLASASY DDTIRLWRED LDDWGQVACI
     KGHQGTVWCV DWEGAENVPS APTDLADDDP VTAQWKKAHA LSGPRLVSCS DDRTVRIWRR
     QPKEQHQHQA QPSPSGGSGI PSIIRPTGSD EFWDEECVLP QAHDLSIYTV AWSKRTGLIA
     SVGADGRVVV YEERFIVGST AEAMETDHPT SADGTAADSP AALRTEWRVI ATVDGAHGIY
     EINHVTWAKR ADRGRIEGTD EEVLITTADD GTVRVWTLKM