ID   CIAO1_BOTFB             Reviewed;         436 AA.
AC   A6RT32;
DT   01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Probable cytosolic iron-sulfur protein assembly protein 1 {ECO:0000255|HAMAP-Rule:MF_03037};
GN   Name=cia1; ORFNames=BC1G_03768;
OS   Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis
OS   cinerea).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Sclerotiniaceae; Botrytis.
OX   NCBI_TaxID=332648;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B05.10;
RX   PubMed=21876677; DOI=10.1371/journal.pgen.1002230;
RA   Amselem J., Cuomo C.A., van Kan J.A.L., Viaud M., Benito E.P., Couloux A.,
RA   Coutinho P.M., de Vries R.P., Dyer P.S., Fillinger S., Fournier E.,
RA   Gout L., Hahn M., Kohn L., Lapalu N., Plummer K.M., Pradier J.-M.,
RA   Quevillon E., Sharon A., Simon A., ten Have A., Tudzynski B., Tudzynski P.,
RA   Wincker P., Andrew M., Anthouard V., Beever R.E., Beffa R., Benoit I.,
RA   Bouzid O., Brault B., Chen Z., Choquer M., Collemare J., Cotton P.,
RA   Danchin E.G., Da Silva C., Gautier A., Giraud C., Giraud T., Gonzalez C.,
RA   Grossetete S., Gueldener U., Henrissat B., Howlett B.J., Kodira C.,
RA   Kretschmer M., Lappartient A., Leroch M., Levis C., Mauceli E.,
RA   Neuveglise C., Oeser B., Pearson M., Poulain J., Poussereau N.,
RA   Quesneville H., Rascle C., Schumacher J., Segurens B., Sexton A., Silva E.,
RA   Sirven C., Soanes D.M., Talbot N.J., Templeton M., Yandava C., Yarden O.,
RA   Zeng Q., Rollins J.A., Lebrun M.-H., Dickman M.;
RT   "Genomic analysis of the necrotrophic fungal pathogens Sclerotinia
RT   sclerotiorum and Botrytis cinerea.";
RL   PLoS Genet. 7:E1002230-E1002230(2011).
CC   -!- FUNCTION: Essential component of the cytosolic iron-sulfur (Fe/S)
CC       protein assembly machinery. Required for the maturation of
CC       extramitochondrial Fe/S proteins. {ECO:0000255|HAMAP-Rule:MF_03037}.
CC   -!- SIMILARITY: Belongs to the WD repeat CIA1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_03037}.
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DR   EMBL; CH476855; EDN20573.1; -; Genomic_DNA.
DR   RefSeq; XP_001557671.1; XM_001557621.1.
DR   AlphaFoldDB; A6RT32; -.
DR   SMR; A6RT32; -.
DR   GeneID; 5438283; -.
DR   KEGG; bfu:BCIN_04g05390; -.
DR   VEuPathDB; FungiDB:Bcin04g05390; -.
DR   OMA; AIWSKSS; -.
DR   OrthoDB; 793298at2759; -.
DR   GO; GO:0097361; C:CIA complex; IEA:InterPro.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.130.10.10; -; 1.
DR   HAMAP; MF_03037; ciao1; 1.
DR   InterPro; IPR028608; CIAO1/Cia1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR19920; PTHR19920; 1.
DR   Pfam; PF00400; WD40; 3.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE   3: Inferred from homology;
KW   Repeat; WD repeat.
FT   CHAIN           1..436
FT                   /note="Probable cytosolic iron-sulfur protein assembly
FT                   protein 1"
FT                   /id="PRO_0000382507"
FT   REPEAT          10..52
FT                   /note="WD 1"
FT   REPEAT          56..100
FT                   /note="WD 2"
FT   REPEAT          147..186
FT                   /note="WD 3"
FT   REPEAT          195..237
FT                   /note="WD 4"
FT   REPEAT          243..297
FT                   /note="WD 5"
FT   REPEAT          328..367
FT                   /note="WD 6"
FT   REPEAT          389..433
FT                   /note="WD 7"
FT   REGION          94..113
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          118..137
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          295..316
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   436 AA;  47857 MW;  2651C2919F98317C CRC64;
     MRLQHLADFK PQAATRAWAS IPNPNGLPLI ATATSDKSVR VYSLNNFTLH STLEGGHERS
     VRSAAWKPGV RTDGALTIAT GSFDATMGIW RRKEDAGNGN GNDGGDGPLE MEIGADGEVS
     KGAQLRRGGE EDEDEGDDWE FSIVLEGHDS EIKNVAYSPS GQWLASCSRD KTIWIWEEIG
     EEGEDEFETV AVLQDHKADV KCVCWRKDDG NGEVLASGSY DDTILLSRED GEGDWETVAT
     LEGHEGTVWN LDWEPEVSMK TESSDESSAP ATPRLLSSSA DMSIRIWSKV PTPPPQNKPS
     YFNPGIPSTM RPGPENETWE CTATLPKVHD LPIYSISWSK QTGRVVSTGG DGKIAIYEEQ
     TKGRNSVGGT IEKEWVVLTV LEGAHGPYEI NHVTWCQRFD NGKKTPDEEM VITTGDDGLT
     KAWCIEENVE ERTLEA