ID   CIAO1_CHAGB             Reviewed;         452 AA.
AC   Q2GP45;
DT   01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-SEP-2009, sequence version 2.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Probable cytosolic iron-sulfur protein assembly protein 1 {ECO:0000255|HAMAP-Rule:MF_03037};
GN   Name=CIA1 {ECO:0000255|HAMAP-Rule:MF_03037}; ORFNames=CHGG_10259;
OS   Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 /
OS   NRRL 1970) (Soil fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium.
OX   NCBI_TaxID=306901;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970;
RX   PubMed=25720678; DOI=10.1128/genomea.00021-15;
RA   Cuomo C.A., Untereiner W.A., Ma L.-J., Grabherr M., Birren B.W.;
RT   "Draft genome sequence of the cellulolytic fungus Chaetomium globosum.";
RL   Genome Announc. 3:E0002115-E0002115(2015).
CC   -!- FUNCTION: Essential component of the cytosolic iron-sulfur (Fe/S)
CC       protein assembly machinery. Required for the maturation of
CC       extramitochondrial Fe/S proteins. {ECO:0000255|HAMAP-Rule:MF_03037}.
CC   -!- SIMILARITY: Belongs to the WD repeat CIA1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_03037}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EAQ83855.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CH408035; EAQ83855.1; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_001228186.1; XM_001228185.1.
DR   AlphaFoldDB; Q2GP45; -.
DR   STRING; 306901.Q2GP45; -.
DR   EnsemblFungi; EAQ83855; EAQ83855; CHGG_10259.
DR   GeneID; 4396999; -.
DR   HOGENOM; CLU_000288_57_8_1; -.
DR   InParanoid; Q2GP45; -.
DR   OrthoDB; 793298at2759; -.
DR   Proteomes; UP000001056; Unassembled WGS sequence.
DR   GO; GO:0097361; C:CIA complex; IEA:InterPro.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.130.10.10; -; 1.
DR   HAMAP; MF_03037; ciao1; 1.
DR   InterPro; IPR028608; CIAO1/Cia1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR19920; PTHR19920; 1.
DR   Pfam; PF00400; WD40; 3.
DR   SMART; SM00320; WD40; 6.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..452
FT                   /note="Probable cytosolic iron-sulfur protein assembly
FT                   protein 1"
FT                   /id="PRO_0000382511"
FT   REPEAT          70..121
FT                   /note="WD 1"
FT   REPEAT          161..200
FT                   /note="WD 2"
FT   REPEAT          213..267
FT                   /note="WD 3"
FT   REPEAT          273..319
FT                   /note="WD 4"
FT   REPEAT          340..379
FT                   /note="WD 5"
FT   REPEAT          411..452
FT                   /note="WD 6"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..21
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   452 AA;  48167 MW;  9F391030FEDA4A80 CRC64;
     MPPPTTPTPN PSIPQKATLT PLPPFQPDLY QRAWSSIPHP TLPLLATGHA KSVTVFSLAT
     LSKHSALTGG HARSVRTVAW QPARGGGTGG GSGGKRLGLV TGSFDATAGL WSFEGDADAA
     AGGGGGGLER EVRMGGGGGG GGESEEEEEV REWEFNLVLE GHENEVKSLA FSPGGQYLAT
     SSRDKSVWIW EDVSSGQGGD DEDEWETVAV LSEHDGDVKA VAWCPSNLPN ARAGVGRQHN
     SSEVLASASY DDTVRVWRED ADGEWVCVAV LEGHGGTVWG LQWEGKERQD GRFPRLMTFS
     AGRVRSRVWT LRVSGFGGVP STMRRSLREE WDCTAVLPKV HTRDVYSVSW SADTGLVAST
     GSDGIIAVYA EESAPEDVAK SGVEGGAENG TSGPKSNWKV LGTITRAHGP YEVNHITWCK
     RFDPGAEHKG KEEMLVTTGD DGVVRPWQVR IS