CIAO1_CHLRE
ID CIAO1_CHLRE Reviewed; 352 AA.
AC A8IZG4;
DT 01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 04-DEC-2007, sequence version 1.
DT 25-MAY-2022, entry version 69.
DE RecName: Full=Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog {ECO:0000255|HAMAP-Rule:MF_03037};
GN ORFNames=CHLREDRAFT_130093;
OS Chlamydomonas reinhardtii (Chlamydomonas smithii).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Chlamydomonadales; Chlamydomonadaceae; Chlamydomonas.
OX NCBI_TaxID=3055;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CC-503, and cw92;
RX PubMed=17932292; DOI=10.1126/science.1143609;
RA Merchant S.S., Prochnik S.E., Vallon O., Harris E.H., Karpowicz S.J.,
RA Witman G.B., Terry A., Salamov A., Fritz-Laylin L.K., Marechal-Drouard L.,
RA Marshall W.F., Qu L.H., Nelson D.R., Sanderfoot A.A., Spalding M.H.,
RA Kapitonov V.V., Ren Q., Ferris P., Lindquist E., Shapiro H., Lucas S.M.,
RA Grimwood J., Schmutz J., Cardol P., Cerutti H., Chanfreau G., Chen C.L.,
RA Cognat V., Croft M.T., Dent R., Dutcher S., Fernandez E., Fukuzawa H.,
RA Gonzalez-Ballester D., Gonzalez-Halphen D., Hallmann A., Hanikenne M.,
RA Hippler M., Inwood W., Jabbari K., Kalanon M., Kuras R., Lefebvre P.A.,
RA Lemaire S.D., Lobanov A.V., Lohr M., Manuell A., Meier I., Mets L.,
RA Mittag M., Mittelmeier T., Moroney J.V., Moseley J., Napoli C.,
RA Nedelcu A.M., Niyogi K., Novoselov S.V., Paulsen I.T., Pazour G.J.,
RA Purton S., Ral J.P., Riano-Pachon D.M., Riekhof W., Rymarquis L.,
RA Schroda M., Stern D., Umen J., Willows R., Wilson N., Zimmer S.L.,
RA Allmer J., Balk J., Bisova K., Chen C.J., Elias M., Gendler K., Hauser C.,
RA Lamb M.R., Ledford H., Long J.C., Minagawa J., Page M.D., Pan J.,
RA Pootakham W., Roje S., Rose A., Stahlberg E., Terauchi A.M., Yang P.,
RA Ball S., Bowler C., Dieckmann C.L., Gladyshev V.N., Green P., Jorgensen R.,
RA Mayfield S., Mueller-Roeber B., Rajamani S., Sayre R.T., Brokstein P.,
RA Dubchak I., Goodstein D., Hornick L., Huang Y.W., Jhaveri J., Luo Y.,
RA Martinez D., Ngau W.C., Otillar B., Poliakov A., Porter A., Szajkowski L.,
RA Werner G., Zhou K., Grigoriev I.V., Rokhsar D.S., Grossman A.R.;
RT "The Chlamydomonas genome reveals the evolution of key animal and plant
RT functions.";
RL Science 318:245-250(2007).
CC -!- FUNCTION: Essential component of the cytosolic iron-sulfur (Fe/S)
CC protein assembly machinery. Required for the maturation of
CC extramitochondrial Fe/S proteins. {ECO:0000255|HAMAP-Rule:MF_03037}.
CC -!- SIMILARITY: Belongs to the WD repeat CIA1 family. {ECO:0000255|HAMAP-
CC Rule:MF_03037}.
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DR EMBL; DS496128; EDP02714.1; -; Genomic_DNA.
DR RefSeq; XP_001694281.1; XM_001694229.1.
DR AlphaFoldDB; A8IZG4; -.
DR SMR; A8IZG4; -.
DR STRING; 3055.EDP02714; -.
DR PaxDb; A8IZG4; -.
DR GeneID; 5719967; -.
DR eggNOG; KOG0645; Eukaryota.
DR HOGENOM; CLU_000288_57_8_1; -.
DR InParanoid; A8IZG4; -.
DR OrthoDB; 793298at2759; -.
DR GO; GO:0097361; C:CIA complex; IEA:InterPro.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-UniRule.
DR Gene3D; 2.130.10.10; -; 2.
DR HAMAP; MF_03037; ciao1; 1.
DR InterPro; IPR028608; CIAO1/Cia1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR19920; PTHR19920; 1.
DR Pfam; PF00400; WD40; 6.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 3.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Repeat; WD repeat.
FT CHAIN 1..352
FT /note="Probable cytosolic iron-sulfur protein assembly
FT protein CIAO1 homolog"
FT /id="PRO_0000382532"
FT REPEAT 14..53
FT /note="WD 1"
FT REPEAT 63..102
FT /note="WD 2"
FT REPEAT 107..146
FT /note="WD 3"
FT REPEAT 152..191
FT /note="WD 4"
FT REPEAT 200..240
FT /note="WD 5"
FT REPEAT 268..306
FT /note="WD 6"
FT REPEAT 319..352
FT /note="WD 7"
SQ SEQUENCE 352 AA; 38513 MW; BD9FF34FD477507F CRC64;
MDPFTLEPIG ALSGHDDRVW NVAWSPQGDM LASCSGDKTV RIWSRRQPRP SEQWYCSAIL
DQCHTRTIRS VAWSPTGRAL ATASFDATVA VWELSSGVWE QVAELEGHEN EVKCVAWNPD
GRLIATCGRD RSVWIWESMP GREFECVDVK QGHSQDVKAV TWHPSGELLV SAGYDDTIKL
WTYDGDEWGC AQTLGGTGTG HESTVWDVCW DPVSRARLAS CSDDLTLRLW ESRAAPTSTP
ASAPAGAAAA GFVPSRPDLR CAVTLSGHHR RTVFSLDWAP TGLIATGDGD DSILAEEEAS
GLLTQPGGQW GCWARVAKAH GADVNCVRWN PAEPRLLASC SDDGLIRLWW LR