CIAO1_CULQU
ID CIAO1_CULQU Reviewed; 338 AA.
AC B0XAF3;
DT 01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 08-APR-2008, sequence version 1.
DT 03-AUG-2022, entry version 71.
DE RecName: Full=Probable cytosolic iron-sulfur protein assembly protein Ciao1 {ECO:0000255|HAMAP-Rule:MF_03037};
GN Name=Ciao1 {ECO:0000255|HAMAP-Rule:MF_03037}; ORFNames=CPIJ016096;
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB;
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.D.,
RA Hannick L.I., Megy K., O'Leary S.B., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C.M., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Essential component of the cytosolic iron-sulfur (Fe/S)
CC protein assembly machinery. Required for the maturation of
CC extramitochondrial Fe/S proteins. {ECO:0000255|HAMAP-Rule:MF_03037}.
CC -!- SIMILARITY: Belongs to the WD repeat CIA1 family. {ECO:0000255|HAMAP-
CC Rule:MF_03037}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS232580; EDS43650.1; -; Genomic_DNA.
DR RefSeq; XP_001866625.1; XM_001866590.1.
DR AlphaFoldDB; B0XAF3; -.
DR SMR; B0XAF3; -.
DR STRING; 7176.CPIJ016096-PA; -.
DR EnsemblMetazoa; XM_001866590.2; XP_001866625.1; LOC6049938.
DR GeneID; 6049938; -.
DR KEGG; cqu:CpipJ_CPIJ016096; -.
DR VEuPathDB; VectorBase:CPIJ016096; -.
DR VEuPathDB; VectorBase:CQUJHB011270; -.
DR eggNOG; KOG0645; Eukaryota.
DR HOGENOM; CLU_000288_57_8_1; -.
DR InParanoid; B0XAF3; -.
DR OMA; AIWSKSS; -.
DR OrthoDB; 793298at2759; -.
DR PhylomeDB; B0XAF3; -.
DR Proteomes; UP000002320; Partially assembled WGS sequence.
DR GO; GO:0097361; C:CIA complex; IEA:InterPro.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
DR Gene3D; 2.130.10.10; -; 1.
DR HAMAP; MF_03037; ciao1; 1.
DR InterPro; IPR028608; CIAO1/Cia1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR19920; PTHR19920; 1.
DR Pfam; PF00400; WD40; 6.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Reference proteome; Repeat; WD repeat.
FT CHAIN 1..338
FT /note="Probable cytosolic iron-sulfur protein assembly
FT protein Ciao1"
FT /id="PRO_0000382482"
FT REPEAT 12..51
FT /note="WD 1"
FT REPEAT 58..97
FT /note="WD 2"
FT REPEAT 102..141
FT /note="WD 3"
FT REPEAT 147..186
FT /note="WD 4"
FT REPEAT 193..232
FT /note="WD 5"
FT REPEAT 234..252
FT /note="WD 6"
FT REPEAT 253..291
FT /note="WD 7"
FT REPEAT 302..338
FT /note="WD 8"
SQ SEQUENCE 338 AA; 37451 MW; 8DC3CD909A6D2921 CRC64;
MGKLTLLQCL SGHRGRVWGA GWHPRDPVLA TCGEDKTIRI WADDGTGRWV PKTVLSDGHT
RTIRDVAWSP CGRFLASASF DATVAIWDRR SGEFECNATL EGHENEVKSV SWSKSGALLA
TCSRDKSVWI WEVAQEDEYE CAAVLNTHSQ DVKKVEWHPN EDVLASASYD NTIQLYREDL
ADSDWSSFDT LASHDSTVWS IAFDASGSRL ASCSDDQTVR IWQEYKPGNE FGVACPDGKT
PVWKCVCTLS GFHSRAVYDI SWCKKTGLIA TACGDDMVRI FREVAGSPAN EPTFEMVASK
HAHSQDANTV EWSPTVAGLL VTTSDDGDVK LWKFEDDE