位置:首页 > 蛋白库 > CIAO1_DANRE
CIAO1_DANRE
ID   CIAO1_DANRE             Reviewed;         330 AA.
AC   Q6P0D9; B0S611; Q803C8;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 126.
DE   RecName: Full=Probable cytosolic iron-sulfur protein assembly protein ciao1 {ECO:0000255|HAMAP-Rule:MF_03037};
DE   AltName: Full=WD repeat-containing protein 39 {ECO:0000255|HAMAP-Rule:MF_03037};
GN   Name=ciao1; Synonyms=wdr39; ORFNames=si:dkey-49H9.1, zgc:55911, zgc:77394;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen;
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA   Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA   Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA   White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA   Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA   Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA   Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA   Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA   Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA   Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA   Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA   McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA   Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA   Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA   Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA   Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA   Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA   Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA   Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA   Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA   Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA   Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA   de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA   Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the human
RT   genome.";
RL   Nature 496:498-503(2013).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=AB; TISSUE=Embryo;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Key component of the cytosolic iron-sulfur protein assembly
CC       (CIA) complex, a multiprotein complex that mediates the incorporation
CC       of iron-sulfur cluster into extramitochondrial Fe/S proteins.
CC       {ECO:0000255|HAMAP-Rule:MF_03037}.
CC   -!- SUBUNIT: Component of the CIA complex. {ECO:0000255|HAMAP-
CC       Rule:MF_03037}.
CC   -!- SIMILARITY: Belongs to the WD repeat CIA1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_03037}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BX323451; CAQ13300.1; -; Genomic_DNA.
DR   EMBL; BC044534; AAH44534.1; -; mRNA.
DR   EMBL; BC065658; AAH65658.1; -; mRNA.
DR   EMBL; BC171538; AAI71538.1; -; mRNA.
DR   EMBL; BC171540; AAI71540.1; -; mRNA.
DR   RefSeq; NP_956441.2; NM_200147.2.
DR   AlphaFoldDB; Q6P0D9; -.
DR   SMR; Q6P0D9; -.
DR   STRING; 7955.ENSDARP00000076693; -.
DR   PaxDb; Q6P0D9; -.
DR   Ensembl; ENSDART00000082256; ENSDARP00000076693; ENSDARG00000059212.
DR   GeneID; 795104; -.
DR   KEGG; dre:795104; -.
DR   CTD; 9391; -.
DR   ZFIN; ZDB-GENE-040426-839; ciao1.
DR   eggNOG; KOG0645; Eukaryota.
DR   GeneTree; ENSGT00940000158670; -.
DR   HOGENOM; CLU_000288_57_8_1; -.
DR   InParanoid; Q6P0D9; -.
DR   OMA; AIWSKSS; -.
DR   OrthoDB; 793298at2759; -.
DR   PhylomeDB; Q6P0D9; -.
DR   TreeFam; TF318181; -.
DR   PRO; PR:Q6P0D9; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 8.
DR   Bgee; ENSDARG00000059212; Expressed in spleen and 27 other tissues.
DR   GO; GO:0097361; C:CIA complex; ISS:UniProtKB.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
DR   GO; GO:0097428; P:protein maturation by iron-sulfur cluster transfer; ISS:UniProtKB.
DR   Gene3D; 2.130.10.10; -; 1.
DR   HAMAP; MF_03037; ciao1; 1.
DR   InterPro; IPR028608; CIAO1/Cia1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR19920; PTHR19920; 1.
DR   Pfam; PF00400; WD40; 6.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 6.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..330
FT                   /note="Probable cytosolic iron-sulfur protein assembly
FT                   protein ciao1"
FT                   /id="PRO_0000281108"
FT   REPEAT          14..53
FT                   /note="WD 1"
FT   REPEAT          59..98
FT                   /note="WD 2"
FT   REPEAT          103..142
FT                   /note="WD 3"
FT   REPEAT          148..187
FT                   /note="WD 4"
FT   REPEAT          192..231
FT                   /note="WD 5"
FT   REPEAT          244..283
FT                   /note="WD 6"
FT   REPEAT          295..330
FT                   /note="WD 7"
FT   CONFLICT        181
FT                   /note="D -> G (in Ref. 2; AAH44534)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        292
FT                   /note="V -> M (in Ref. 2; AAH44534)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   330 AA;  36803 MW;  63232ADD0D153162 CRC64;
     MKGALELQHR VSAHPDSRCW YVAWNPAGTT LATCGGDRAI RIWGKEGDSW ECKCVLSDGH
     QRTVRKVAWS PCGKYLASAS FDATTCIWKK TDEDFECLTV LEGHENEVKC VAWAPSGSLL
     ATCSRDKSVW IWEVDEEDEY ECLSVVNSHT QDVKHVVWHP TQELLASASY DNKICIYKEE
     DDDWECRATL EGHESTVWSL TFDPEGRRLA SCSDDRTVKI WKESTTGDGS SDESWKCICT
     LSGFHGRTIY DIAWCRLTGA LATACGDDGV RVFSEDPTAD PEQPIFALSA HVPKAHNQDV
     NCVSWNPKEA GLLATCSDNG EFAIWKYNSA
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024