ID   CIAO1_DROAN             Reviewed;         335 AA.
AC   B3MC74;
DT   01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=Probable cytosolic iron-sulfur protein assembly protein Ciao1 {ECO:0000255|HAMAP-Rule:MF_03037};
GN   Name=Ciao1 {ECO:0000255|HAMAP-Rule:MF_03037}; ORFNames=GF12085;
OS   Drosophila ananassae (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7217;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 14024-0371.13;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- FUNCTION: Essential component of the cytosolic iron-sulfur (Fe/S)
CC       protein assembly machinery. Required for the maturation of
CC       extramitochondrial Fe/S proteins. {ECO:0000255|HAMAP-Rule:MF_03037}.
CC   -!- SIMILARITY: Belongs to the WD repeat CIA1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_03037}.
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DR   EMBL; CH902619; EDV36174.1; -; Genomic_DNA.
DR   RefSeq; XP_001959352.1; XM_001959316.2.
DR   AlphaFoldDB; B3MC74; -.
DR   SMR; B3MC74; -.
DR   STRING; 7217.FBpp0115277; -.
DR   EnsemblMetazoa; FBtr0116785; FBpp0115277; FBgn0089124.
DR   GeneID; 6494943; -.
DR   KEGG; dan:6494943; -.
DR   eggNOG; KOG0645; Eukaryota.
DR   HOGENOM; CLU_000288_57_8_1; -.
DR   InParanoid; B3MC74; -.
DR   OMA; AIWSKSS; -.
DR   OrthoDB; 793298at2759; -.
DR   PhylomeDB; B3MC74; -.
DR   Proteomes; UP000007801; Unassembled WGS sequence.
DR   GO; GO:0097361; C:CIA complex; IEA:InterPro.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
DR   Gene3D; 2.130.10.10; -; 1.
DR   HAMAP; MF_03037; ciao1; 1.
DR   InterPro; IPR028608; CIAO1/Cia1.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR19920; PTHR19920; 1.
DR   Pfam; PF00400; WD40; 7.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 6.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..335
FT                   /note="Probable cytosolic iron-sulfur protein assembly
FT                   protein Ciao1"
FT                   /id="PRO_0000382483"
FT   REPEAT          12..51
FT                   /note="WD 1"
FT   REPEAT          57..96
FT                   /note="WD 2"
FT   REPEAT          101..140
FT                   /note="WD 3"
FT   REPEAT          146..185
FT                   /note="WD 4"
FT   REPEAT          192..231
FT                   /note="WD 5"
FT   REPEAT          250..289
FT                   /note="WD 6"
FT   REPEAT          301..335
FT                   /note="WD 7"
SQ   SEQUENCE   335 AA;  37198 MW;  1969D06E38AF9A94 CRC64;
     MGRLNLEHTL QGHKGRIWGV AWHPKGNVFA SCGEDKAIRI WSLNGNTWTT KTILSDGHKR
     TIREIRWSPC GQYLASASFD GTTAIWSKSS GEFECNATLE GHENEVKSVS WSRSGGLLAT
     CSRDKSVWIW EVAGDDEFEC AAVLNPHTQD VKRVVWHPTK ELLASASYDN TIKMFAEDAL
     DSDWDCVATL SSHTSTVWSI DFDATGERLV SCSDDTSLKI WQAYHPGNDA GVATPDKQTV
     WKCVCTISGQ HSRAIYDVSW CKLTNLIATA CGDDGIRIFK ETSDSKRDEP TFEQLTAEEG
     AHDQDVNSVE WNPVVEGQLI SCSDDGTIKV WKMTE