CIAO1_EMENI
ID CIAO1_EMENI Reviewed; 446 AA.
AC Q5BDJ5; C8VRU0;
DT 01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 19-OCT-2011, sequence version 2.
DT 25-MAY-2022, entry version 110.
DE RecName: Full=Probable cytosolic iron-sulfur protein assembly protein 1 {ECO:0000255|HAMAP-Rule:MF_03037};
GN Name=cia1; ORFNames=AN1385;
OS Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS M139) (Aspergillus nidulans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Nidulantes.
OX NCBI_TaxID=227321;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=16372000; DOI=10.1038/nature04341;
RA Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT fumigatus and A. oryzae.";
RL Nature 438:1105-1115(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA Oliver S.G., Turner G.;
RT "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT effort.";
RL Fungal Genet. Biol. 46:S2-13(2009).
CC -!- FUNCTION: Essential component of the cytosolic iron-sulfur (Fe/S)
CC protein assembly machinery. Required for the maturation of
CC extramitochondrial Fe/S proteins. {ECO:0000255|HAMAP-Rule:MF_03037}.
CC -!- SIMILARITY: Belongs to the WD repeat CIA1 family. {ECO:0000255|HAMAP-
CC Rule:MF_03037}.
CC -!- CAUTION: It is uncertain whether Met-1 or Met-2 is the initiator.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=EAA65215.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AACD01000019; EAA65215.1; ALT_INIT; Genomic_DNA.
DR EMBL; BN001308; CBF87600.1; -; Genomic_DNA.
DR RefSeq; XP_658989.1; XM_653897.1.
DR AlphaFoldDB; Q5BDJ5; -.
DR SMR; Q5BDJ5; -.
DR STRING; 162425.CADANIAP00001222; -.
DR EnsemblFungi; CBF87600; CBF87600; ANIA_01385.
DR EnsemblFungi; EAA65215; EAA65215; AN1385.2.
DR GeneID; 2877158; -.
DR KEGG; ani:AN1385.2; -.
DR VEuPathDB; FungiDB:AN1385; -.
DR eggNOG; KOG0645; Eukaryota.
DR HOGENOM; CLU_000288_57_8_1; -.
DR InParanoid; Q5BDJ5; -.
DR OMA; AIWSKSS; -.
DR OrthoDB; 793298at2759; -.
DR Proteomes; UP000000560; Chromosome VIII.
DR Proteomes; UP000005890; Unassembled WGS sequence.
DR GO; GO:0097361; C:CIA complex; IBA:GO_Central.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; IBA:GO_Central.
DR Gene3D; 2.130.10.10; -; 1.
DR HAMAP; MF_03037; ciao1; 1.
DR InterPro; IPR028608; CIAO1/Cia1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR19920; PTHR19920; 1.
DR Pfam; PF00400; WD40; 3.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Reference proteome; Repeat; WD repeat.
FT CHAIN 1..446
FT /note="Probable cytosolic iron-sulfur protein assembly
FT protein 1"
FT /id="PRO_0000382515"
FT REPEAT 22..64
FT /note="WD 1"
FT REPEAT 68..110
FT /note="WD 2"
FT REPEAT 144..183
FT /note="WD 3"
FT REPEAT 191..230
FT /note="WD 4"
FT REPEAT 235..300
FT /note="WD 5"
FT REPEAT 328..367
FT /note="WD 6"
FT REPEAT 402..446
FT /note="WD 7"
SQ SEQUENCE 446 AA; 49425 MW; 3FE05F126866F2B5 CRC64;
MMTAPNVVQS SPSLALSFLS DLTPPSLERT WLTAPHPTLP LVATCSSDKT VRVYSLVNFR
LLSTISGGHK RSIRTCAWKP NVSGESVLAT GSFDATVGIW RRWDDYGEEE TLAQGNKNTK
NFGAEEDREE DEDDEWRFAV LLDGHDSEVK SVSWSASGML LATCSRDKSI WIWEDLEDGD
NNFETVAVMQ EHEGDVKCVA WHPAEECLAS GSYDDTIRIW REDIDDWGQV ACIKGHTGTV
WGIDWEDAEN VPFPSTSNGV SGQEEEWKTW HALSGPRLVS CSHDQSVRVW RRQPKAQLNT
AGASSIPSII RPSGTDETWE EDVVLPHAHE LPIYAVAWSR RTGLLASVGA DGRLVVYEER
FVSSHTKPQA MNTDEVSPNL GEGVCAPHPS TEWSIVAVVN GAHGIYEINH VAWAKRADRG
RDGNKEEEVL ITTADDGSIK VWTLTR
