ID   CIAO1_MALGO             Reviewed;         356 AA.
AC   A8PWQ8;
DT   01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Probable cytosolic iron-sulfur protein assembly protein 1 {ECO:0000255|HAMAP-Rule:MF_03037};
GN   Name=CIA1 {ECO:0000255|HAMAP-Rule:MF_03037}; ORFNames=MGL_1185;
OS   Malassezia globosa (strain ATCC MYA-4612 / CBS 7966) (Dandruff-associated
OS   fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Malasseziomycetes; Malasseziales; Malasseziaceae; Malassezia.
OX   NCBI_TaxID=425265;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4612 / CBS 7966;
RX   PubMed=18000048; DOI=10.1073/pnas.0706756104;
RA   Xu J., Saunders C.W., Hu P., Grant R.A., Boekhout T., Kuramae E.E.,
RA   Kronstad J.W., DeAngelis Y.M., Reeder N.L., Johnstone K.R., Leland M.,
RA   Fieno A.M., Begley W.M., Sun Y., Lacey M.P., Chaudhary T., Keough T.,
RA   Chu L., Sears R., Yuan B., Dawson T.L. Jr.;
RT   "Dandruff-associated Malassezia genomes reveal convergent and divergent
RT   virulence traits shared with plant and human fungal pathogens.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:18730-18735(2007).
CC   -!- FUNCTION: Essential component of the cytosolic iron-sulfur (Fe/S)
CC       protein assembly machinery. Required for the maturation of
CC       extramitochondrial Fe/S proteins. {ECO:0000255|HAMAP-Rule:MF_03037}.
CC   -!- SIMILARITY: Belongs to the WD repeat CIA1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_03037}.
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DR   EMBL; AAYY01000003; EDP44703.1; -; Genomic_DNA.
DR   RefSeq; XP_001731917.1; XM_001731865.1.
DR   AlphaFoldDB; A8PWQ8; -.
DR   SMR; A8PWQ8; -.
DR   STRING; 425265.A8PWQ8; -.
DR   EnsemblFungi; EDP44703; EDP44703; MGL_1185.
DR   GeneID; 5856222; -.
DR   KEGG; mgl:MGL_1185; -.
DR   VEuPathDB; FungiDB:MGL_1185; -.
DR   InParanoid; A8PWQ8; -.
DR   OMA; AIWSKSS; -.
DR   OrthoDB; 793298at2759; -.
DR   Proteomes; UP000008837; Unassembled WGS sequence.
DR   GO; GO:0097361; C:CIA complex; IEA:InterPro.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.130.10.10; -; 1.
DR   HAMAP; MF_03037; ciao1; 1.
DR   InterPro; IPR028608; CIAO1/Cia1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR19920; PTHR19920; 1.
DR   Pfam; PF00400; WD40; 5.
DR   SMART; SM00320; WD40; 6.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 5.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..356
FT                   /note="Probable cytosolic iron-sulfur protein assembly
FT                   protein 1"
FT                   /id="PRO_0000382519"
FT   REPEAT          34..73
FT                   /note="WD 1"
FT   REPEAT          89..128
FT                   /note="WD 2"
FT   REPEAT          134..173
FT                   /note="WD 3"
FT   REPEAT          179..218
FT                   /note="WD 4"
FT   REPEAT          244..291
FT                   /note="WD 5"
FT   REPEAT          319..356
FT                   /note="WD 6"
SQ   SEQUENCE   356 AA;  39156 MW;  58D4BE8B73214592 CRC64;
     MSQQNTVEGG FDLSSGVSDK KEWVFNLQEV IPTGHKRTVR SVAWSPNGEV LATASFDSTV
     GLWERIPENI RAEEGSDGPE WECFGTLEGH DSECKSVAFS YNGNLLASCG RDKSVWVWEA
     QPDADYECIG VLIEHSQDVK CVIWHPKEEI LASASYDNTI KMYVDDPSCD WYCYTTLQAH
     SSTVWSLSFS PCGQFLASSS DDMTIWIWRR VSAAECVELG IQAHGNTPGR SGERWVPTYC
     IQGHFSGPIF SVNWAPGDSF DPRQALGKLV AAGADGKIIV FFLVRIYATL RGTYACAQSL
     EDNNPSRIFV HVGAQEENAH GSVDVNCVKW APMNTDGSAP TMIASAGDDG EIRIWT