ID   CIAO1_SCLS1             Reviewed;         452 AA.
AC   A7EZJ5;
DT   01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Probable cytosolic iron-sulfur protein assembly protein 1 {ECO:0000255|HAMAP-Rule:MF_03037};
GN   Name=cia1; ORFNames=SS1G_10762;
OS   Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold)
OS   (Whetzelinia sclerotiorum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Sclerotiniaceae; Sclerotinia.
OX   NCBI_TaxID=665079;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 18683 / 1980 / Ss-1;
RX   PubMed=21876677; DOI=10.1371/journal.pgen.1002230;
RA   Amselem J., Cuomo C.A., van Kan J.A.L., Viaud M., Benito E.P., Couloux A.,
RA   Coutinho P.M., de Vries R.P., Dyer P.S., Fillinger S., Fournier E.,
RA   Gout L., Hahn M., Kohn L., Lapalu N., Plummer K.M., Pradier J.-M.,
RA   Quevillon E., Sharon A., Simon A., ten Have A., Tudzynski B., Tudzynski P.,
RA   Wincker P., Andrew M., Anthouard V., Beever R.E., Beffa R., Benoit I.,
RA   Bouzid O., Brault B., Chen Z., Choquer M., Collemare J., Cotton P.,
RA   Danchin E.G., Da Silva C., Gautier A., Giraud C., Giraud T., Gonzalez C.,
RA   Grossetete S., Gueldener U., Henrissat B., Howlett B.J., Kodira C.,
RA   Kretschmer M., Lappartient A., Leroch M., Levis C., Mauceli E.,
RA   Neuveglise C., Oeser B., Pearson M., Poulain J., Poussereau N.,
RA   Quesneville H., Rascle C., Schumacher J., Segurens B., Sexton A., Silva E.,
RA   Sirven C., Soanes D.M., Talbot N.J., Templeton M., Yandava C., Yarden O.,
RA   Zeng Q., Rollins J.A., Lebrun M.-H., Dickman M.;
RT   "Genomic analysis of the necrotrophic fungal pathogens Sclerotinia
RT   sclerotiorum and Botrytis cinerea.";
RL   PLoS Genet. 7:E1002230-E1002230(2011).
CC   -!- FUNCTION: Essential component of the cytosolic iron-sulfur (Fe/S)
CC       protein assembly machinery. Required for the maturation of
CC       extramitochondrial Fe/S proteins. {ECO:0000255|HAMAP-Rule:MF_03037}.
CC   -!- SIMILARITY: Belongs to the WD repeat CIA1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_03037}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CH476636; EDN94887.1; -; Genomic_DNA.
DR   RefSeq; XP_001588315.1; XM_001588265.1.
DR   AlphaFoldDB; A7EZJ5; -.
DR   SMR; A7EZJ5; -.
DR   STRING; 665079.A7EZJ5; -.
DR   GeneID; 5484197; -.
DR   KEGG; ssl:SS1G_10762; -.
DR   VEuPathDB; FungiDB:sscle_09g070090; -.
DR   InParanoid; A7EZJ5; -.
DR   OMA; NHVCWAL; -.
DR   Proteomes; UP000001312; Unassembled WGS sequence.
DR   GO; GO:0097361; C:CIA complex; IBA:GO_Central.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 1.
DR   HAMAP; MF_03037; ciao1; 1.
DR   InterPro; IPR028608; CIAO1/Cia1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR19920; PTHR19920; 1.
DR   Pfam; PF00400; WD40; 3.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..452
FT                   /note="Probable cytosolic iron-sulfur protein assembly
FT                   protein 1"
FT                   /id="PRO_0000382526"
FT   REPEAT          20..59
FT                   /note="WD 1"
FT   REPEAT          63..118
FT                   /note="WD 2"
FT   REPEAT          163..202
FT                   /note="WD 3"
FT   REPEAT          211..253
FT                   /note="WD 4"
FT   REPEAT          259..313
FT                   /note="WD 5"
FT   REPEAT          344..383
FT                   /note="WD 6"
FT   REPEAT          405..449
FT                   /note="WD 7"
FT   REGION          112..153
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   452 AA;  49864 MW;  D92103522A5D0DE9 CRC64;
     MPSSLPTMIL KHLADFKPQA ATRAWASIPN PNNLPLIATA TSDKSVRVYS LSNFTLHSKL
     EGGHERSVRS AAWKPGVRKD GALTLATGGF DTMMTIATGS FDATMGVWRR KEEQKNTIED
     GPLELEIGAD GRPNKGPSLR RGGDDGSDED EGDDWEFSIV LEGHDSEIKH VAYSPSGQWL
     ASCSRDKTIW IWEEIGDEGE DEFETVAVLQ DHTADVKCVC WRKDDGNGEV LASGSYDDTI
     LLSKEDGEGD WETIAKLEGH DGTVWSLDWE PDVSIKSDSS EESSVPPTPR LLSSSADMTV
     RIWSKMPTPP PQNKPSYFNA GIPSTMRPGP VNETWECTAT LPKVHDLPVY SINWSKYSGR
     IVSTGGDGRV AIYEERTKGR NTVGGTIEKE WVVLTVLEGA HGPYEVNHVT WCMRYDNGKK
     KPDEEMIITT GDDGLTKAWF IEEDIEESKV EA