ID   CIAO1_USTMA             Reviewed;         455 AA.
AC   Q4P5F5; A0A0D1CLJ0;
DT   01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=Probable cytosolic iron-sulfur protein assembly protein 1 {ECO:0000255|HAMAP-Rule:MF_03037};
GN   Name=CIA1 {ECO:0000255|HAMAP-Rule:MF_03037}; ORFNames=UMAG_04658;
OS   Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX   NCBI_TaxID=237631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=521 / FGSC 9021;
RX   PubMed=17080091; DOI=10.1038/nature05248;
RA   Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., Saville B.J.,
RA   Banuett F., Kronstad J.W., Gold S.E., Mueller O., Perlin M.H.,
RA   Woesten H.A.B., de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G.,
RA   Snetselaar K., McCann M., Perez-Martin J., Feldbruegge M., Basse C.W.,
RA   Steinberg G., Ibeas J.I., Holloman W., Guzman P., Farman M.L.,
RA   Stajich J.E., Sentandreu R., Gonzalez-Prieto J.M., Kennell J.C., Molina L.,
RA   Schirawski J., Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N.,
RA   Scherer M., Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B.,
RA   Meng S., Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA   Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA   Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA   Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA   Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., Muensterkoetter M.,
RA   Haase D., Oesterheld M., Mewes H.-W., Mauceli E.W., DeCaprio D., Wade C.M.,
RA   Butler J., Young S.K., Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E.,
RA   Birren B.W.;
RT   "Insights from the genome of the biotrophic fungal plant pathogen Ustilago
RT   maydis.";
RL   Nature 444:97-101(2006).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=521 / FGSC 9021;
RA   Gueldener U., Muensterkoetter M., Walter M.C., Mannhaupt G., Kahmann R.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Essential component of the cytosolic iron-sulfur (Fe/S)
CC       protein assembly machinery. Required for the maturation of
CC       extramitochondrial Fe/S proteins. {ECO:0000255|HAMAP-Rule:MF_03037}.
CC   -!- SIMILARITY: Belongs to the WD repeat CIA1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_03037}.
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DR   EMBL; CM003152; KIS67563.1; -; Genomic_DNA.
DR   RefSeq; XP_011390936.1; XM_011392634.1.
DR   AlphaFoldDB; Q4P5F5; -.
DR   SMR; Q4P5F5; -.
DR   STRING; 5270.UM04658P0; -.
DR   EnsemblFungi; KIS67563; KIS67563; UMAG_04658.
DR   GeneID; 23564767; -.
DR   KEGG; uma:UMAG_04658; -.
DR   VEuPathDB; FungiDB:UMAG_04658; -.
DR   eggNOG; KOG0645; Eukaryota.
DR   HOGENOM; CLU_000288_57_8_1; -.
DR   InParanoid; Q4P5F5; -.
DR   OMA; AIWSKSS; -.
DR   OrthoDB; 793298at2759; -.
DR   Proteomes; UP000000561; Chromosome 13.
DR   GO; GO:0097361; C:CIA complex; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IEA:EnsemblFungi.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IBA:GO_Central.
DR   GO; GO:0097428; P:protein maturation by iron-sulfur cluster transfer; IEA:EnsemblFungi.
DR   GO; GO:0002098; P:tRNA wobble uridine modification; IEA:EnsemblFungi.
DR   Gene3D; 2.130.10.10; -; 1.
DR   HAMAP; MF_03037; ciao1; 1.
DR   InterPro; IPR028608; CIAO1/Cia1.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR19920; PTHR19920; 1.
DR   Pfam; PF00400; WD40; 6.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 5.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..455
FT                   /note="Probable cytosolic iron-sulfur protein assembly
FT                   protein 1"
FT                   /id="PRO_0000382527"
FT   REPEAT          31..70
FT                   /note="WD 1"
FT   REPEAT          90..129
FT                   /note="WD 2"
FT   REPEAT          163..202
FT                   /note="WD 3"
FT   REPEAT          208..247
FT                   /note="WD 4"
FT   REPEAT          253..292
FT                   /note="WD 5"
FT   REPEAT          318..365
FT                   /note="WD 6"
FT   REPEAT          380..453
FT                   /note="WD 7"
SQ   SEQUENCE   455 AA;  49199 MW;  E08198D344784567 CRC64;
     MTTMTTAAAK AAEPTRTTAI ASLHLLAELE GHSSRAWHLA WNPRMPILAS CSGDKDVRLH
     AYSFVSTTSA QGASTCKHPS FNLREVIPTG HQRTVRQVAW SPDGKILATA SFDSTVGIWE
     RIQDIDGSSE LQGNTDASGP VVLSNGGAHV DEPEWDCVGT LEGHESECKS VAFSYTGGVL
     ASCSRDKSVW IWEVQPDAEF ECLSVLMEHS QDVKVVAWHP NDEVLASASY DDAIKLYIDD
     PSDDWFCYTT LTGHESTVWS ISFSPCGNYL ASASDDLTVR IWRRLDADQC EAHGLRPEGK
     MAGRRGEKWI AVNILNGYHD RTVYSVSWGV DKTSTRPGNL GRIASGGGDG RICVYEVTAS
     DDEKSLQPKV ELIAKMERAH ASADVNCVSW APESLNARGG TTAKIEQLTD EGETLNKGGQ
     HASHELMSDM LASAGDDGSV KVWTLASSAY AATSK