CID10_ARATH
ID CID10_ARATH Reviewed; 353 AA.
AC Q9SG10; Q0WQ17;
DT 14-MAY-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 143.
DE RecName: Full=Polyadenylate-binding protein-interacting protein 10;
DE Short=PABP-interacting protein 10;
DE Short=Poly(A)-binding protein-interacting protein 10;
DE AltName: Full=PAM2-containing protein CID10;
DE AltName: Full=Protein CTC-INTERACTING DOMAIN 10;
GN Name=CID10; OrderedLocusNames=At3g49390; ORFNames=F2K15.250, T1G12.9;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia; TISSUE=Root;
RX PubMed=19423640; DOI=10.1093/dnares/dsp009;
RA Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M.,
RA Shinozaki K.;
RT "Analysis of multiple occurrences of alternative splicing events in
RT Arabidopsis thaliana using novel sequenced full-length cDNAs.";
RL DNA Res. 16:155-164(2009).
RN [5]
RP GENE FAMILY, PAM2 MOTIF, AND TISSUE SPECIFICITY.
RX PubMed=15650869; DOI=10.1007/s00438-004-1090-9;
RA Bravo J., Aguilar-Henonin L., Olmedo G., Guzman P.;
RT "Four distinct classes of proteins as interaction partners of the PABC
RT domain of Arabidopsis thaliana Poly(A)-binding proteins.";
RL Mol. Genet. Genomics 272:651-665(2005).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in cauline leaves, stems, rosette leaves,
CC immature siliques and primary inflorescences.
CC {ECO:0000269|PubMed:15650869}.
CC -!- DOMAIN: Contains a PAM2-like motif, which seems to be involved in the
CC binding to the PABC/CTC domain of PAB proteins.
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DR EMBL; AC012329; AAG52182.1; -; Genomic_DNA.
DR EMBL; AL132956; CAB66418.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE78535.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE78536.1; -; Genomic_DNA.
DR EMBL; CP002686; ANM63369.1; -; Genomic_DNA.
DR EMBL; AK228892; BAF00782.1; -; mRNA.
DR EMBL; AK317338; BAH20012.1; -; mRNA.
DR PIR; T45844; T45844.
DR RefSeq; NP_001030833.1; NM_001035756.2.
DR RefSeq; NP_001325461.1; NM_001339409.1.
DR RefSeq; NP_190508.1; NM_114799.4.
DR AlphaFoldDB; Q9SG10; -.
DR SMR; Q9SG10; -.
DR STRING; 3702.AT3G49390.2; -.
DR PaxDb; Q9SG10; -.
DR PRIDE; Q9SG10; -.
DR ProteomicsDB; 246938; -.
DR EnsemblPlants; AT3G49390.1; AT3G49390.1; AT3G49390.
DR EnsemblPlants; AT3G49390.2; AT3G49390.2; AT3G49390.
DR EnsemblPlants; AT3G49390.3; AT3G49390.3; AT3G49390.
DR GeneID; 824101; -.
DR Gramene; AT3G49390.1; AT3G49390.1; AT3G49390.
DR Gramene; AT3G49390.2; AT3G49390.2; AT3G49390.
DR Gramene; AT3G49390.3; AT3G49390.3; AT3G49390.
DR KEGG; ath:AT3G49390; -.
DR Araport; AT3G49390; -.
DR TAIR; locus:2082961; AT3G49390.
DR eggNOG; KOG0118; Eukaryota.
DR HOGENOM; CLU_042473_2_1_1; -.
DR InParanoid; Q9SG10; -.
DR OMA; VFINCGQ; -.
DR OrthoDB; 943794at2759; -.
DR PhylomeDB; Q9SG10; -.
DR PRO; PR:Q9SG10; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9SG10; baseline and differential.
DR Genevisible; Q9SG10; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003729; F:mRNA binding; IDA:TAIR.
DR CDD; cd12459; RRM1_CID8_like; 1.
DR CDD; cd12460; RRM2_CID8_like; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR009818; Ataxin-2_C.
DR InterPro; IPR034823; CID8-like_RRM1.
DR InterPro; IPR034825; CID8-like_RRM2.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR Pfam; PF07145; PAM2; 1.
DR Pfam; PF00076; RRM_1; 2.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; SSF54928; 2.
DR PROSITE; PS50102; RRM; 2.
PE 2: Evidence at transcript level;
KW Nucleus; Reference proteome; Repeat; RNA-binding.
FT CHAIN 1..353
FT /note="Polyadenylate-binding protein-interacting protein
FT 10"
FT /id="PRO_0000428900"
FT DOMAIN 169..244
FT /note="RRM 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT DOMAIN 266..341
FT /note="RRM 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT REGION 1..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 128..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 96..106
FT /note="PAM2-like"
FT MOTIF 142..153
FT /note="Bipartite nuclear localization signal"
FT /evidence="ECO:0000255"
FT COMPBIAS 10..56
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 289
FT /note="L -> P (in Ref. 3; BAF00782)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 353 AA; 38738 MW; 44A33938E7F3FB59 CRC64;
MAVAENAGVK VDSSGQNLDN NNTAASATET TKPPCPDDDQ SPKSDSSTPL TIDSTPETDD
RINETAQKVQ TLNGFSGNGE RDNNGEIKDL ADAFSKLNPM AQEFVPPSLA RSQSGVLRNG
LGFTNNFAAP PKLADGNDHF PRRRRSFGQG KRRMNKRTSL AQKDDVIRRT VYVSDIDQQV
TEENLAGVFI NCGQVVDCRV CGDPNSVLRF AFIEFTNEEG ARAALSMSGT VLGFYPLKVL
PSKTAIAPVN PTFLPRSEDE REMCVRTVYC TNIDKRITQI DLKGFFEMLC GEVHRLRLGD
YHHQTRIAFV EFAMAESAIA ALHCSGIVLG ALPIRVSPSK TPVRPHFPRA EFK