ID   CID3_ARATH              Reviewed;         587 AA.
AC   Q8L793; Q9SYH5;
DT   14-MAY-2014, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=Polyadenylate-binding protein-interacting protein 3;
DE            Short=PABP-interacting protein 3;
DE            Short=Poly(A)-binding protein-interacting protein 3;
DE   AltName: Full=PAM2-containing protein CID3;
DE   AltName: Full=Protein CTC-INTERACTING DOMAIN 3;
GN   Name=CID3; OrderedLocusNames=At1g54170; ORFNames=F15I1.27;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   GENE FAMILY, AND PAM2 MOTIF.
RX   PubMed=15650869; DOI=10.1007/s00438-004-1090-9;
RA   Bravo J., Aguilar-Henonin L., Olmedo G., Guzman P.;
RT   "Four distinct classes of proteins as interaction partners of the PABC
RT   domain of Arabidopsis thaliana Poly(A)-binding proteins.";
RL   Mol. Genet. Genomics 272:651-665(2005).
CC   -!- DOMAIN: Contains a tandem repeat of a PAM2-like motif, which seems to
CC       be involved in the binding to the PABC/CTC domain of PAB proteins.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAD25791.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AC006577; AAD25791.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002684; AEE33057.1; -; Genomic_DNA.
DR   EMBL; AY136398; AAM97064.1; -; mRNA.
DR   EMBL; BT000204; AAN15523.1; -; mRNA.
DR   PIR; H96582; H96582.
DR   RefSeq; NP_175819.1; NM_104295.4.
DR   AlphaFoldDB; Q8L793; -.
DR   SMR; Q8L793; -.
DR   BioGRID; 27082; 1.
DR   IntAct; Q8L793; 1.
DR   STRING; 3702.AT1G54170.1; -.
DR   iPTMnet; Q8L793; -.
DR   PaxDb; Q8L793; -.
DR   PRIDE; Q8L793; -.
DR   ProteomicsDB; 246906; -.
DR   EnsemblPlants; AT1G54170.1; AT1G54170.1; AT1G54170.
DR   GeneID; 841857; -.
DR   Gramene; AT1G54170.1; AT1G54170.1; AT1G54170.
DR   KEGG; ath:AT1G54170; -.
DR   Araport; AT1G54170; -.
DR   TAIR; locus:2014330; AT1G54170.
DR   eggNOG; KOG2375; Eukaryota.
DR   HOGENOM; CLU_022637_0_0_1; -.
DR   InParanoid; Q8L793; -.
DR   OMA; SRSHYPE; -.
DR   OrthoDB; 581631at2759; -.
DR   PhylomeDB; Q8L793; -.
DR   PRO; PR:Q8L793; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q8L793; baseline and differential.
DR   Genevisible; Q8L793; AT.
DR   GO; GO:0010494; C:cytoplasmic stress granule; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0034063; P:stress granule assembly; IBA:GO_Central.
DR   InterPro; IPR009818; Ataxin-2_C.
DR   InterPro; IPR045117; ATXN2-like.
DR   InterPro; IPR009604; LsmAD_domain.
DR   InterPro; IPR025852; SM_dom_ATX.
DR   PANTHER; PTHR12854; PTHR12854; 1.
DR   Pfam; PF06741; LsmAD; 1.
DR   Pfam; PF07145; PAM2; 1.
DR   Pfam; PF14438; SM-ATX; 1.
DR   SMART; SM01272; LsmAD; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Repeat.
FT   CHAIN           1..587
FT                   /note="Polyadenylate-binding protein-interacting protein 3"
FT                   /id="PRO_0000428894"
FT   REGION          422..503
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           467..475
FT                   /note="PAM2-like 1; degenerate"
FT   MOTIF           476..486
FT                   /note="PAM2-like 2"
FT   COMPBIAS        422..501
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   587 AA;  65389 MW;  A419F0BA40E521DC CRC64;
     MKPVLHSGSS SNGFSHRRFE KEAWMNNAQP SVDNTENGWD AESVDTPSQK LLVYFTTCNI
     GHQVEVHLKN GSVYSGIFHA ANVEKDFGII LKMACLIRDS RGTKSRTVSK PSSKLLKIPA
     DELVQVIAKD LPLSSDSVSD SVQCEKPLEL LTDSLISQFY NVDLERELKP WVPDEDVPDC
     SDLENVFDDP WKRGWNQFEV NKTLFGVTST FDEELYTTKL ERGPGTRELE EQALRIAREI
     VGENTRDIHV AEERGLQLSG KFDIDEETKY SSVCATNRFD DTCYEDDEEE EEDILLDCCN
     NLTFGDSSAS DGKEPASTGK FYEDSWGDSL HLRSNKMVDQ SWSNSNKHTR QLMSELPSKD
     FPVAGNNIRN ESQLGEQRKS KFLGASLFKK PSEESVSGFE DAPPPVKPSF IDGRLGLLSD
     RAKSENSSGW PGSSISRNSE NSAASSASNL PILSPSSSGS LSSEKSTLNP NAKEFKLNPN
     AKSFKPSPSA TRPQSPQSPV FDGSFYYPPV PPMPGLHIRY GTGAAFPGQQ HPMMYNNTTQ
     LSPNQTYYSP NSPQYPQPMM VTQQRPILFM PPTPYQPEMP YKGRDSY