ID   CIGA_DICDI              Reviewed;         814 AA.
AC   P14606; Q54J67;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   04-DEC-2007, sequence version 2.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Cyclic AMP-inducible protein BP74;
DE   Flags: Precursor;
GN   Name=cigA; ORFNames=DDB_G0288245;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=AX3;
RX   PubMed=2555685; DOI=10.1128/mcb.9.10.4170-4178.1989;
RA   Hopkinson S.B., Pollenz R.S., Drummond I., Chisholm R.L.;
RT   "Expression and organization of BP74, a cyclic AMP-regulated gene expressed
RT   during Dictyostelium discoideum development.";
RL   Mol. Cell. Biol. 9:4170-4178(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- INDUCTION: By cAMP.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA33168.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=AAA33168.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; M29237; AAA33168.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AAFI02000109; EAL63304.1; -; Genomic_DNA.
DR   PIR; A34095; A34095.
DR   RefSeq; XP_636820.1; XM_631728.1.
DR   AlphaFoldDB; P14606; -.
DR   STRING; 44689.DDB0191118; -.
DR   PaxDb; P14606; -.
DR   PRIDE; P14606; -.
DR   EnsemblProtists; EAL63304; EAL63304; DDB_G0288245.
DR   GeneID; 8626538; -.
DR   KEGG; ddi:DDB_G0288245; -.
DR   dictyBase; DDB_G0288245; cigA.
DR   HOGENOM; CLU_346983_0_0_1; -.
DR   InParanoid; P14606; -.
DR   PhylomeDB; P14606; -.
DR   PRO; PR:P14606; -.
DR   Proteomes; UP000002195; Chromosome 5.
PE   2: Evidence at transcript level;
KW   Coiled coil; Reference proteome; Repeat; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..814
FT                   /note="Cyclic AMP-inducible protein BP74"
FT                   /id="PRO_0000020930"
FT   REGION          149..757
FT                   /note="26 X tandem repeats"
FT   COILED          754..787
FT                   /evidence="ECO:0000255"
FT   CONFLICT        261..262
FT                   /note="EI -> GV (in Ref. 1; AAA33168)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        397
FT                   /note="I -> T (in Ref. 1; AAA33168)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        602
FT                   /note="E -> G (in Ref. 1; AAA33168)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        625
FT                   /note="K -> E (in Ref. 1; AAA33168)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        646
FT                   /note="Missing (in Ref. 1; AAA33168)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        727
FT                   /note="N -> K (in Ref. 1; AAA33168)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   814 AA;  97668 MW;  98952FDF80E60F07 CRC64;
     MNKFYSLPLI IILIISCGAF FIHGEEAYFE YRIHNEKFIF KLSDDIKIQH ARRVLSGDEI
     SLTNVVGKII NKPIEYNINW DFHLDPDSVT FFESETEFCN QKFQYVNGYI DKLCESDNCY
     FCPWDGSLVR ELYFGDIKQD LLLRNNENQQ VKQVYEGDIK QDLIRRKNKI HPEKQMHEED
     IKQQVFFRIK NIHEKPVYEG DIKQDLLRRK NKNNPEKQVY EGDIKQDLLR RKYYDKSQST
     QVYQGDVIQD ILRSINRQEK EIYEGDIKQD LLRRNNQNNQ EKQVYESDIK QDILRRKYYE
     KSQSTQVYQG DMTQDILRSL NRQEKGVYEG DIKQDLLRRK YYDKSQSNQV YQGDVIQDIL
     RSINRDKKPV YEGDIKQDLL LRNNQNPQEK SIYEGDIKQD ILRRKNLDKS QSIQFYPGDI
     IQDILRVLNR EEKEVYDGDI KQDLLSRKNL AKYQSTEVYP GDVIQDVLRV LNHDEKEVYE
     VDIKQDLLRR NNKNPQEKPV YEGDIKQDIL RRNNLDKSQP KQVYPGDTIQ DILRIINRDE
     KVYEGDIKQD LSGRKNHQEK TVYEGDIKQD LLRRKNLDKP DSKQVYPGDV IQDILRVINR
     DEKEVYEGDI KQDLLHRNNK NRQEKPVYEG DIKQDLLRRN NKNHQEEQVY QGDIIQDILR
     VLNHEEKEVY EGDIKQNLLR RKNHDHPEKE IYEGDIKQDL LRRNNKNHQE KLVYEGDIKQ
     DLLRRNNKNH KEEQVYQGDI IQDILRVLNH GEKEVNEDEI EKDLMQRKNH HQEEEASEDL
     EEEIGKLWNK QSQAFVEQHP NQHNNQKTIH LSRQ