ID   ACG_MYCTO               Reviewed;         331 AA.
AC   P9WIZ8; L0TB56; O53476; Q7D7L2;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 32.
DE   RecName: Full=Putative NAD(P)H nitroreductase acg;
DE            EC=1.-.-.-;
GN   Name=acg; OrderedLocusNames=MT2091;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- COFACTOR:
CC       Name=FMN; Xref=ChEBI:CHEBI:58210; Evidence={ECO:0000305};
CC   -!- SIMILARITY: Belongs to the nitroreductase family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAK46370.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE000516; AAK46370.1; ALT_INIT; Genomic_DNA.
DR   PIR; G70942; G70942.
DR   RefSeq; WP_003410193.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WIZ8; -.
DR   SMR; P9WIZ8; -.
DR   EnsemblBacteria; AAK46370; AAK46370; MT2091.
DR   KEGG; mtc:MT2091; -.
DR   PATRIC; fig|83331.31.peg.2256; -.
DR   HOGENOM; CLU_051479_1_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.109.10; -; 2.
DR   InterPro; IPR000415; Nitroreductase-like.
DR   SUPFAM; SSF55469; SSF55469; 2.
PE   3: Inferred from homology;
KW   Flavoprotein; FMN; NAD; NADP; Oxidoreductase.
FT   CHAIN           1..331
FT                   /note="Putative NAD(P)H nitroreductase acg"
FT                   /id="PRO_0000427917"
FT   BINDING         28..32
FT                   /ligand="FMN"
FT                   /ligand_id="ChEBI:CHEBI:58210"
FT                   /evidence="ECO:0000255"
FT   BINDING         316
FT                   /ligand="FMN"
FT                   /ligand_id="ChEBI:CHEBI:58210"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   331 AA;  36559 MW;  8FF2A825CE90C6EB CRC64;
     MPDTMVTTDV IKSAVQLACR APSLHNSQPW RWIAEDHTVA LFLDKDRVLY ATDHSGREAL
     LGCGAVLDHF RVAMAAAGTT ANVERFPNPN DPLHLASIDF SPADFVTEGH RLRADAILLR
     RTDRLPFAEP PDWDLVESQL RTTVTADTVR IDVIADDMRP ELAAASKLTE SLRLYDSSYH
     AELFWWTGAF ETSEGIPHSS LVSAAESDRV TFGRDFPVVA NTDRRPEFGH DRSKVLVLST
     YDNERASLLR CGEMLSAVLL DATMAGLATC TLTHITELHA SRDLVAALIG QPATPQALVR
     VGLAPEMEEP PPATPRRPID EVFHVRAKDH R