CIO1A_SALSA
ID CIO1A_SALSA Reviewed; 330 AA.
AC B5X9P2;
DT 01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 25-NOV-2008, sequence version 1.
DT 03-AUG-2022, entry version 45.
DE RecName: Full=Probable cytosolic iron-sulfur protein assembly protein ciao1-A {ECO:0000255|HAMAP-Rule:MF_03037};
DE AltName: Full=WD repeat-containing protein 39-A {ECO:0000255|HAMAP-Rule:MF_03037};
GN Name=ciao1a;
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Thyroid;
RX PubMed=20433749; DOI=10.1186/1471-2164-11-279;
RA Leong J.S., Jantzen S.G., von Schalburg K.R., Cooper G.A., Messmer A.M.,
RA Liao N.Y., Munro S., Moore R., Holt R.A., Jones S.J., Davidson W.S.,
RA Koop B.F.;
RT "Salmo salar and Esox lucius full-length cDNA sequences reveal changes in
RT evolutionary pressures on a post-tetraploidization genome.";
RL BMC Genomics 11:279-279(2010).
CC -!- FUNCTION: Key component of the cytosolic iron-sulfur protein assembly
CC (CIA) complex, a multiprotein complex that mediates the incorporation
CC of iron-sulfur cluster into extramitochondrial Fe/S proteins.
CC {ECO:0000255|HAMAP-Rule:MF_03037}.
CC -!- SUBUNIT: Component of the CIA complex. {ECO:0000255|HAMAP-
CC Rule:MF_03037}.
CC -!- SIMILARITY: Belongs to the WD repeat CIA1 family. {ECO:0000255|HAMAP-
CC Rule:MF_03037}.
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DR EMBL; BT047761; ACI67562.1; -; mRNA.
DR RefSeq; XP_014015694.1; XM_014160219.1.
DR AlphaFoldDB; B5X9P2; -.
DR SMR; B5X9P2; -.
DR STRING; 8030.ENSSSAP00000082324; -.
DR GeneID; 106579887; -.
DR KEGG; sasa:106579887; -.
DR OMA; AIWSKSS; -.
DR OrthoDB; 793298at2759; -.
DR Proteomes; UP000087266; Chromosome ssa20.
DR Bgee; ENSSSAG00000067814; Expressed in sexually immature organism and 16 other tissues.
DR GO; GO:0097361; C:CIA complex; ISS:UniProtKB.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
DR Gene3D; 2.130.10.10; -; 1.
DR HAMAP; MF_03037; ciao1; 1.
DR InterPro; IPR028608; CIAO1/Cia1.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR19920; PTHR19920; 1.
DR Pfam; PF00400; WD40; 6.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; Repeat; WD repeat.
FT CHAIN 1..330
FT /note="Probable cytosolic iron-sulfur protein assembly
FT protein ciao1-A"
FT /id="PRO_0000382477"
FT REPEAT 14..53
FT /note="WD 1"
FT REPEAT 59..98
FT /note="WD 2"
FT REPEAT 103..142
FT /note="WD 3"
FT REPEAT 148..187
FT /note="WD 4"
FT REPEAT 192..231
FT /note="WD 5"
FT REPEAT 243..282
FT /note="WD 6"
FT REPEAT 294..330
FT /note="WD 7"
SQ SEQUENCE 330 AA; 36818 MW; 27B50DD586566362 CRC64;
MKDTLALLQK FNAHPDSRCW YVAWNPKGTL LASCGGDRAI RIWGREGDSW ECKTVLQDGH
QRAVRKVAWS PCGNYLASAS FDATTCIWKK KNDDFECLTV LEGHENEVKC VAWAPSGNQL
ATCSRDKSVW IWEVDEEDEY ECVSVVNSHT QDVKHVVWHP TQELLASCSY DNNVCVYKEE
DDDWECRATL EGHTSTVWGL TFDPSGQRLA SCSDDRTVKI WKECQPGGGQ DTAWKCVCTL
SGFHGRTVYD IAWCPLTGAL ATACGDDGVR VFKEDETADP DQPVFSLSAH VPKAHSQDVN
CIAWHPKEAG LLVSCSDNGE IAVWNYQSEV
