CIO1B_SALSA
ID CIO1B_SALSA Reviewed; 333 AA.
AC B5X212;
DT 01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 25-NOV-2008, sequence version 1.
DT 03-AUG-2022, entry version 44.
DE RecName: Full=Probable cytosolic iron-sulfur protein assembly protein ciao1-B {ECO:0000255|HAMAP-Rule:MF_03037};
DE AltName: Full=WD repeat-containing protein 39-B {ECO:0000255|HAMAP-Rule:MF_03037};
GN Name=ciao1b;
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=20433749; DOI=10.1186/1471-2164-11-279;
RA Leong J.S., Jantzen S.G., von Schalburg K.R., Cooper G.A., Messmer A.M.,
RA Liao N.Y., Munro S., Moore R., Holt R.A., Jones S.J., Davidson W.S.,
RA Koop B.F.;
RT "Salmo salar and Esox lucius full-length cDNA sequences reveal changes in
RT evolutionary pressures on a post-tetraploidization genome.";
RL BMC Genomics 11:279-279(2010).
CC -!- FUNCTION: Key component of the cytosolic iron-sulfur protein assembly
CC (CIA) complex, a multiprotein complex that mediates the incorporation
CC of iron-sulfur cluster into extramitochondrial Fe/S proteins.
CC {ECO:0000255|HAMAP-Rule:MF_03037}.
CC -!- SUBUNIT: Component of the CIA complex. {ECO:0000255|HAMAP-
CC Rule:MF_03037}.
CC -!- SIMILARITY: Belongs to the WD repeat CIA1 family. {ECO:0000255|HAMAP-
CC Rule:MF_03037}.
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DR EMBL; BT045081; ACI33343.1; -; mRNA.
DR RefSeq; XP_014027367.1; XM_014171892.1.
DR AlphaFoldDB; B5X212; -.
DR SMR; B5X212; -.
DR STRING; 8030.ENSSSAP00000117557; -.
DR PRIDE; B5X212; -.
DR GeneID; 106585549; -.
DR KEGG; sasa:106585549; -.
DR OMA; DDWECAA; -.
DR OrthoDB; 793298at2759; -.
DR Proteomes; UP000087266; Chromosome ssa24.
DR Bgee; ENSSSAG00000080516; Expressed in mesonephros and 16 other tissues.
DR GO; GO:0097361; C:CIA complex; ISS:UniProtKB.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
DR Gene3D; 2.130.10.10; -; 1.
DR HAMAP; MF_03037; ciao1; 1.
DR InterPro; IPR028608; CIAO1/Cia1.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR19920; PTHR19920; 1.
DR Pfam; PF00400; WD40; 6.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; Repeat; WD repeat.
FT CHAIN 1..333
FT /note="Probable cytosolic iron-sulfur protein assembly
FT protein ciao1-B"
FT /id="PRO_0000382478"
FT REPEAT 14..53
FT /note="WD 1"
FT REPEAT 59..98
FT /note="WD 2"
FT REPEAT 103..142
FT /note="WD 3"
FT REPEAT 148..187
FT /note="WD 4"
FT REPEAT 192..231
FT /note="WD 5"
FT REPEAT 246..285
FT /note="WD 6"
FT REPEAT 297..333
FT /note="WD 7"
SQ SEQUENCE 333 AA; 37038 MW; F8ACC3163413F908 CRC64;
MNDTLALLQK FNAHPDSRCW YVAWNPKGTL LASCGGDRTI RIWGREGDSW ECKTVLQDGH
QRTVRKVAWS PCGNYLASAS FDATTCIWKK KNDDFECLTV LEGHENEVKC VAWAPSGNLL
ATCSRDKSVW IWEVDEENEY ECVSVVNSHT QDVKHVVWHP TQELLASCSY DNNVCVYKEE
DDDWECRATL EGHTSTVWGL TFDPSGQRLA SCSDDCTVKI WKECQPEGGQ EGTDAAWKCV
CTLSGFHGRT VYDIAWCPLT GALATACGDD GVRVFKEDET ADPDQPAFSL SAHVPKAHTQ
DVNCIAWHPK EAGLLVSCSD NGEIAVWNYQ SGV
