ID   CIS1_ASHGO              Reviewed;         142 AA.
AC   Q755V9;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Autophagy-related protein 31;
DE   AltName: Full=Protein CIS1;
GN   Name=CIS1; Synonyms=ATG31; OrderedLocusNames=AER409C;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Plays a role in starvation-induced autophagy. Involved in
CC       mitophagy. Functions with ATG17 and ATG29 at the preautophagosomal
CC       structure (PAS) in order to form normal autophagosomes under starvation
CC       conditions. May be involved in microtubule function, such as chromosome
CC       segregation and karyogamy (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000305}.
CC       Preautophagosomal structure {ECO:0000250}.
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DR   EMBL; AE016818; AAS53088.1; -; Genomic_DNA.
DR   RefSeq; NP_985264.1; NM_210618.1.
DR   AlphaFoldDB; Q755V9; -.
DR   SMR; Q755V9; -.
DR   STRING; 33169.AAS53088; -.
DR   EnsemblFungi; AAS53088; AAS53088; AGOS_AER409C.
DR   GeneID; 4621480; -.
DR   KEGG; ago:AGOS_AER409C; -.
DR   HOGENOM; CLU_138108_0_0_1; -.
DR   InParanoid; Q755V9; -.
DR   OMA; IRYIFED; -.
DR   Proteomes; UP000000591; Chromosome V.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0000407; C:phagophore assembly site; IEA:UniProtKB-SubCell.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0000741; P:karyogamy; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR018621; Atg31.
DR   Pfam; PF09795; ATG31; 1.
PE   3: Inferred from homology;
KW   Autophagy; Chromosome partition; Cytoplasm; Cytoskeleton; Karyogamy;
KW   Microtubule; Protein transport; Reference proteome; Transport.
FT   CHAIN           1..142
FT                   /note="Autophagy-related protein 31"
FT                   /id="PRO_0000076208"
SQ   SEQUENCE   142 AA;  16139 MW;  B31A98C01D7A0CB3 CRC64;
     MEPFVITASE CDCNSAHSSR VSKDGYALSD ELSNETMFLT QVKYIFEGEE DHIDDNTMQE
     INTDIVNVVI VELDETLEIK NVELISDEYQ LLGFSNDADN DLNLTILSEF PADVSPGTRD
     LGKLVTRYQH QNKHLKHMLQ EL