ID   CIS1_CANGA              Reviewed;         182 AA.
AC   Q6FM20;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Autophagy-related protein 31;
DE   AltName: Full=Protein CIS1;
GN   Name=CIS1; Synonyms=ATG31; OrderedLocusNames=CAGL0K11682g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Plays a role in starvation-induced autophagy. Involved in
CC       mitophagy. Functions with ATG17 and ATG29 at the preautophagosomal
CC       structure (PAS) in order to form normal autophagosomes under starvation
CC       conditions. May be involved in microtubule function, such as chromosome
CC       segregation and karyogamy (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000305}.
CC       Preautophagosomal structure {ECO:0000250}.
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DR   EMBL; CR380957; CAG61687.1; -; Genomic_DNA.
DR   RefSeq; XP_448724.1; XM_448724.1.
DR   AlphaFoldDB; Q6FM20; -.
DR   SMR; Q6FM20; -.
DR   STRING; 5478.XP_448724.1; -.
DR   EnsemblFungi; CAG61687; CAG61687; CAGL0K11682g.
DR   GeneID; 2890527; -.
DR   KEGG; cgr:CAGL0K11682g; -.
DR   CGD; CAL0134281; CAGL0K11682g.
DR   VEuPathDB; FungiDB:CAGL0K11682g; -.
DR   eggNOG; ENOG502SA9V; Eukaryota.
DR   HOGENOM; CLU_138108_0_0_1; -.
DR   InParanoid; Q6FM20; -.
DR   Proteomes; UP000002428; Chromosome K.
DR   GO; GO:1990316; C:Atg1/ULK1 kinase complex; IEA:EnsemblFungi.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0000407; C:phagophore assembly site; IEA:UniProtKB-SubCell.
DR   GO; GO:0000422; P:autophagy of mitochondrion; IEA:EnsemblFungi.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0000741; P:karyogamy; IEA:UniProtKB-KW.
DR   GO; GO:0044805; P:late nucleophagy; IEA:EnsemblFungi.
DR   GO; GO:0034727; P:piecemeal microautophagy of the nucleus; IEA:EnsemblFungi.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR018621; Atg31.
DR   Pfam; PF09795; ATG31; 1.
PE   3: Inferred from homology;
KW   Autophagy; Chromosome partition; Cytoplasm; Cytoskeleton; Karyogamy;
KW   Microtubule; Protein transport; Reference proteome; Transport.
FT   CHAIN           1..182
FT                   /note="Autophagy-related protein 31"
FT                   /id="PRO_0000076209"
FT   REGION          105..134
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   182 AA;  20611 MW;  D94FC37EF6BAE322 CRC64;
     MEPLSLTVYD RNIWHLFKKE EGAPQAMFPT NIKYIFEDDD DVADVDDLVF QQQQPDSELE
     NVIIVEIDGA GQLENVELIS DQYEMLSYRR ERPVSLASQR SLSWLTSGND TGGDAGKKSG
     DISDPAAGPD VPREAPLSIE LELVSEFKDY RNLNLEDLKL DELTRIFCIQ NKQLQMISDA
     LN