ID   28KD_MYCLE              Reviewed;         236 AA.
AC   P19361;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=28 kDa antigen;
DE   Flags: Precursor;
GN   OrderedLocusNames=ML0091;
OS   Mycobacterium leprae (strain TN).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=272631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3058804;
RA   Cherayil B.J., Young R.A.;
RT   "A 28-kDa protein from Mycobacterium leprae is a target of the human
RT   antibody response in lepromatous leprosy.";
RL   J. Immunol. 141:4370-4375(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TN;
RX   PubMed=11234002; DOI=10.1038/35059006;
RA   Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA   Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA   Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA   Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA   Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA   Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA   Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA   Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA   Barrell B.G.;
RT   "Massive gene decay in the leprosy bacillus.";
RL   Nature 409:1007-1011(2001).
CC   -!- SIMILARITY: To M.tuberculosis ERP. {ECO:0000305}.
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DR   EMBL; M23232; AAA25345.1; -; Genomic_DNA.
DR   EMBL; AL583917; CAC29599.1; -; Genomic_DNA.
DR   PIR; A30557; A30557.
DR   RefSeq; NP_301189.1; NC_002677.1.
DR   RefSeq; WP_010907514.1; NC_002677.1.
DR   AlphaFoldDB; P19361; -.
DR   STRING; 272631.ML0091; -.
DR   EnsemblBacteria; CAC29599; CAC29599; CAC29599.
DR   KEGG; mle:ML0091; -.
DR   PATRIC; fig|272631.5.peg.144; -.
DR   Leproma; ML0091; -.
DR   eggNOG; ENOG50334MW; Bacteria.
DR   HOGENOM; CLU_063439_0_0_11; -.
DR   OMA; NKAPEHH; -.
DR   Proteomes; UP000000806; Chromosome.
PE   4: Predicted;
KW   Reference proteome; Signal.
FT   SIGNAL          1..22
FT   CHAIN           23..236
FT                   /note="28 kDa antigen"
FT                   /id="PRO_0000020574"
FT   REGION          76..105
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   236 AA;  23784 MW;  5A9760D06ADACDFB CRC64;
     MPNRRRCKLS TAISTVATLA IASPCAYFLV YEPTASAKPA AKHYEFKQAA SIADLPGEVL
     DAISQGLSQF GINLPPVPSL TGTDDPGNGL RTPGLTSPDL TNQELGTPVL TAPGTGLTPP
     VTGSPICTAP DLNLGGTCPS EVPITTPISL DPGTDGTYPI LGDPSTLGGT SPISTSSGEL
     VNDLLKVANQ LGASQVMDLI KGVVMPAVMQ GVQNGNVAGD LSGSVTPAAI SLIPVT