ID   CITE2_XENLA             Reviewed;         225 AA.
AC   Q5XGW7;
DT   19-JAN-2010, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 53.
DE   RecName: Full=Cbp/p300-interacting transactivator 2 {ECO:0000250|UniProtKB:Q99967};
GN   Name=cited2;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1] {ECO:0000312|EMBL:AAH84310.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Gastrula {ECO:0000312|EMBL:AAH84310.1};
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transcriptional coactivator or corepressor of the p300/CBP-
CC       mediated transcription complex. May be involved in sex determination,
CC       early gonad development, left-right patterning during embryogenesis and
CC       differentiation of the adrenal cortex (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q99967}.
CC   -!- SIMILARITY: Belongs to the CITED family. {ECO:0000255}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC084310; AAH84310.1; -; mRNA.
DR   RefSeq; NP_001088289.1; NM_001094820.1.
DR   AlphaFoldDB; Q5XGW7; -.
DR   BioGRID; 105204; 1.
DR   MaxQB; Q5XGW7; -.
DR   DNASU; 495124; -.
DR   GeneID; 495124; -.
DR   KEGG; xla:495124; -.
DR   CTD; 495124; -.
DR   Xenbase; XB-GENE-866410; cited2.L.
DR   OMA; HAMGPGN; -.
DR   OrthoDB; 1378769at2759; -.
DR   Proteomes; UP000186698; Chromosome 5L.
DR   Bgee; 495124; Expressed in egg cell and 19 other tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR007576; CITED.
DR   PANTHER; PTHR17045; PTHR17045; 1.
DR   Pfam; PF04487; CITED; 1.
PE   2: Evidence at transcript level;
KW   Activator; Developmental protein; Differentiation; Nucleus;
KW   Reference proteome; Repressor; Transcription; Transcription regulation.
FT   CHAIN           1..225
FT                   /note="Cbp/p300-interacting transactivator 2"
FT                   /id="PRO_0000390735"
SQ   SEQUENCE   225 AA;  25184 MW;  13A8E71D6755573D CRC64;
     MADHMMAMNH SRFQDGTNGL HHPAHRMGMG QFPSPHHHQH TFNSLMGEHM HYVPGNMNSN
     NSIRHAMVTG NVNGGHPNGS IAPAARFNNS QFMGPPVTNQ GAQLTASMQL QKLNNQYFTH
     QPYPHNHYIP DLHPTNHPLN GTNQHFKECN PKHSTGLPPS VSHVPAAILP PGVIDTDFID
     EEVLMSLVIE MGLDRIKELP ELWLGQNEFD FMTDFVCKQP NRVSC